Im wondering what relation my father's cousin (my grandfather's brother's son) would be to me...?? And would there be any problems later on down the track when we get married and decide to have children???
Your father's first cousin is your first cousin once removed. Consanguinity refers to when both members of a couple are related to each other by at least one common ancestor. First cousins once removed are considered 4th degree relatives and share 1/16 of their genes.
We all have two copies of almost every gene - one from each parent. In autosomal recessive (AR) conditions, it is typically necessary to have two mutations, one in each gene copy, to be affected. People with only a mutation in a single gene are called carriers, and typically do not have any symptoms of the condition.
It is believed that we all are carriers of at least 8-10 different autosomal recessive conditions. The chance that both members of a couple are both carriers of the same AR condition is increased if they are related to one another, as they each could have inherited a mutation from the same common ancestor.
To give some background information, the general population risk for two non-related people to have a child with a birth defect is estimated at 3-4%. In the absence of a known autosomal recessive condition in a family, the risk for first cousins to have a child with a birth defect is believed to be doubled, 6-8%. The risk for 4th degree relatives to have a child with a birth defect (again; without a known AR condition in the family) may be considered in between the general population risk and the first cousin risk. In a family with a known AR condition, this risk may be even higher.
We recommend that you meet with a genetic counselor, who can better assess risk based on ethnicity, family history and personal history. A genetic counselor can discuss the benefits and limitations of all available genetic testing options. You can find a genetic counselor at the National Society of Genetic Counselors Website or through companies like mine, AccessDNA.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.