GENETIC DISORDERS EXPERT FORUM
chromosome translocation

chromosome translocation

Hello, after 5 miscarriages, we got to know that my husband has a reciprocal translocation between chromosome 11 and 22. i underwent one pgd session that resulted in a neutral reading (no results were given on 8 embryos). now we have given up doing the pgd for a while.
my question is, what are my chances of having a natural pregnancy without pgd, knowing that my husband is a crrier of this translocated chromosome?
thank you so much for your advice.
Related Discussions
886824_tn?1253740254
We are sorry for your losses and lack of useful information from PGD. In about 5% of couples with recurrent pregnancy losses, one member has a chromosome translocation.

The risk to have an adverse pregnancy outcome or a child with a chromosome abnormality is based on the exact chromosome translocation (for example - the exact break points) and which member of the couple (mom or dad) has the translocation. We recommend that you meet with a genetic counselor, who provide a more accurate risk assessment based on your husband's exact chromosome translocation between chromosomes 11 and 22 and family history. We wish you and your husband the best.
1 Comment
Blank
1306537_tn?1273253382
A related discussion, balanced translocation 7 & 18 was started.
Blank
Avatar_f_tn
A related discussion, TRANSLOCATION 9 AND 13 was started.
Blank
Continue discussion Blank
Go
MedHelp Health Answers
Submit
Blank
Weight Tracker
Reach your weight goal faster
Start Tracking Now
RSS Expert Activity
1741471_tn?1329053231
Blank
Love, endorphins and biochemistry. ... Blank
Feb 15 by Michael Gonzalez-WallaceBlank
1684282_tn?1311133646
Blank
Pregnancy and Addiction
Feb 14 by Julia M Aharonov, DOBlank
514494_tn?1329196433
Blank
What's the Best Type of Mattress?
Feb 13 by Adam Tanase, D.C.Blank