Genetic Disorders Expert Forum
having kids with my second cousin?
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having kids with my second cousin?

i was just wondering if i have kids with my second cousin, what are the chances of there being complications and will the unborn child be normal?? please reply
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Consanguinity refers to when both members of a couple are related to each other by at least one common ancestor.

We all have two copies of almost every gene - one from each parent. In autosomal recessive (AR) conditions, it is typically necessary to have two mutations, one in each gene copy, to be affected. People with only a mutation in a single gene are called carriers, and typically do not have any symptoms of the condition.

It is believed that we all are carriers of at least 8-10 different autosomal recessive conditions. The chance that both members of a couple are both carriers of the same AR condition is increased if they are related to one another, as they each could have inherited a mutation from the same common ancestor.

To give some background information, the general population risk for two non-related people to have a child with a birth defect is estimated at 3-4%. In the absence of a known autosomal recessive condition in a family, the risk for first cousins to have a child with a birth defect is believed to be doubled, 6-8%.

We recommend that you and your partner meet with a genetic counselor, who can review your ethnic backgrounds, as well as your personal and family health histories to provide risk assessment specific to your situation. A genetic counselor can also discuss the benefits and limitations of any available genetic testing options. You can find a genetic counselor through the National Society of Genetic Counseling website or through companies like mine, AccessDNA.  You can also find more information about consanguinity at AccessDNA.
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I have a question. I have found out that my boyfriend is my mothers first cousins son. What does that make us & if we continue our relationship what kinds of risks are there in us having children?
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