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Paternal and Maternal Genetics re Cadasil
My father died from CADASIL a few years ago. I have had the genetic testing for the disease and do not have the mutated gene. I have heard from relatives that it may only be passed down by your mother. Is there any truth to this?
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Hi,
How are you? CADASIL  or Cerebral Autosomal Dominant Arteriopathy with Sub-cortical Infarcts and Leukoencephalopathy,  is an inherited form of cerebrovascular disease that occurs when the thickening of blood vessel walls blocks the flow of blood to the brain. It is an autosomal dominant inheritance disorder, meaning that one parent carries and passes on the defective gene. Most individuals with CADASIL have a family history of the disorder. ( ref: http://www.ninds.nih.gov/disorders/cadasil/CADASIL.htm)
Take care and regards.
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