Robertsonian Translocation 14/21

I am wondering if there is anyone in this community that has a Robertsonian Translocation with Chromosome 14/21? I carry this genetic disorder and so does my mother, brother and sister.  Would love to hear your story.

[crackedegg]

Did you ever find what you were looking for?  I have Robertsonian Translocation 14/21 and so does my father, uncle, aunt and grandmother.  I wish I could tell you my story is a good one, but I have had one miscarriage and a failed ivf with pgd.  We only had 1 "healthy" embryo to implant and although it implanted it must not have had the proper genetic combination.  We are going to begin trying naturally again and hope for the best.

[martikadragoon]

The 14/21 translocation happens to typically be a balanced translocation. Normally as far as I know an Unbalanced translocation results in T21 or Down Syndrome.

in Robertsonian translocation the risk for a child with down syndrome or an Unbalanced translocation is %25. I know this because my child has "typical" T21. But during research for DS I came across this related disorder. Robertsonian Translocation accounts for 4-5% of down syndrome cases.
If the mom is the carier the risk for a baby is %12 if it's the father it's %3....

I know I don't have translocation but I love talking to other parents.  have any of your siblings or your mother had a child with T21 translocation?

TTYL
Cindie

[martikadragoon]

Lol.... srry for the original quote of %25 ... I meant to delete that (I was thinking something else srry) as I mentioned the risk is %12 for a woman and %3 for a man if they have the balanced form of translocation

[jade1711]

i also carry the translocation 14/21 and have had 2 babies perfectly healthy as far as i am aware all my family are carriers but no one in 5 gerations has downs or any other illness.i was told my chances are 1 in 10 for all my pregnancies.hope this helps.