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Genetics  (Expert Forum)
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is polycythemia vera hereditary?
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AccessDNA
Welcome to the Genetics Forum! Questions in the Genetics Forum are being answered by genetic experts from AccessDNA. This forum is for questions and support regarding a person’s predisposition to a variety of medical conditions such as Ashkenazi Jewish Diseases, Bleeding Disorders, Blood Clotting Disorders, Cancer Genetics and Hereditary Cancer Syndromes, Chromosome Abnormalities, Congenital Birth Defects, Cystic Fibrosis, Family History, Fragile X Syndrome, Infertility, Newborn Screening, Rare Genetic Disorders, Prenatal Screening and Testing. This forum is for questions and support regarding a person’s predisposition to a variety of medical conditions such as Alzheimer’s Disease, Blood-clotting Disorders, Breast Cancer, Cystic Fibrosis, Diabetes, Marfan Syndrome, Ehlers-Danlos Syndrome, etc.

is polycythemia vera hereditary?

by dana503, Jul 02, 2009 06:58PM
My grandmother has polycythemia vera and my mom died of cancer....are they related and is the pcv hereditary? (thinking about the lack of control of the stopping mechanism in cell development.)

by Jordanna Joaquina, MS, CGC, Jul 08, 2009 01:18PM
To: dana503
Most cases of polycythemia vera appeared to be caused by sporadic, somatic mutations as opposed to inherited mutations. Most cells in our body divide to make new cells. The DNA in those cells needs to be replicated for each new cell. Sporadic DNA changes can occur during cell division or DNA replication as well as with environment damage.

Cancer is a multifactorial condition, which means that it involves a combination of genetic and non-genetic factors. Some types of cancer have a stronger genetic component than others. You may benefit from meeting with a cancer genetic counselor to discuss your family history. A genetic counselor can be found at the National Society of Genetic Counselors website or through companies like mine, AccessDNA.
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