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Gynecology  (Expert Forum)
 | 
RHESUS IMMUNIZATION
Answered by
Elaine Brown, MD - Pregnancy, Gynecology
Elaine Brown, MD - BLOG Billings - MT
This forum is for questions and support regarding gynecology issues such as: Cervical Disorders, Colposcopy, Cramps, Cystitis, Fallopian Tube Disorders, Menstruation, Ovarian Disorders, PAP Test, Pelvic Exam, PID, PMS, Surgery, Tests, Ultrasound, Uterine Disorders, Vaginal Disorders.

RHESUS IMMUNIZATION

by uttamgovind, Oct 26, 2009 01:37PM
CAN THE INDIRECT COOMBS TEST BE NEGATIVE IN A RH NEG MOTHER DURING HER SECOND PREGNANCY(16WEEKS GESTATION) , 4 YEARS AFTER HER FIRST BABY WHO IS RH POS AND SHE WAS NOT GIVEN ANTI D IN THE FIRST PREGNANCY?

by Elaine Brown, MD, Oct 30, 2009 11:32AM
To: uttamgovind
Hi!
Yes, it can, and that is obviously a very good thing!  It will be important to re-check at approximately 28 weeks to be sure that nothing has changed.  Sometimes a person who is sensitized will have an undetectable antibody level early on, but as the antigenic load increases ( the baby grows more blood cells ) the antibody titre rises.  In other cases the person may not be sensitized--obviously this is the best option!
Good luck!
Dr B
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