This forum is for questions and discussions relating to HIV exposure and risks, living with HIV, HIV prevention, HIV testing, HIV transmission, HIV treatment. All questions will be answered by a medical expert from FreedomHealth.
What if I was exposed to HIV one time 10 years ago and no serocoversion took place. Could the virus lay dormant in my body and suddently reactivate itself after 10 years, du to some sort of mutation of the virus?. Is it at all possible?
I have red that frequently exposed seronegatives people sometimes have HIV virus found in their cells in a very, very small concentration. In this case could they suddenly become seropositive? Due to virus activation, mutation?
If you are not frequently exposed to the virus, is it still possible to have the virus in a very very small ammount, same as the frequently exposed? Or would you have to be exposed many many times?
If I only had one ore possibly two exposure to the HIV-virus years ago, could I have the virus in my cells in a very small amount and not test positive today? I mean what if I aborted the infection du to my resiliens to the virus but the virus didn't die but just went occult?
The medical papers about occult HIV, transient HIV, exposed seronegatives and so on. Have their findings been validated?
Thank you for your post.
I am afaid that all that is a myth.
If someone becomes infected, the virus gets into the bloodstream and replicates, affecting the white blood cells. It does not remain dormant or hidden. The immune response of our bodies with the production of specific antibodies would affect the extent of the viral replication and hence the viral load. Individuals with a normal immune system and without interference of drugs like anti-retrovirals would always present with HIV virus and antibodies in their blood. If this had been your case, you would be able to detect the virus now.
Seroconversion is the production of antibodies by the immune system and in some cases, though extremely rare, patients might not produce antibodies. However if they have been infected thay would always have detectable virus in the bloodstream, i.e. p24 antigen, RNA or DNA. These are independent of the immune response. Therefore one way or another, the infection would always be detectable.
Exactly. As the immune system produces antibodies, these will link to the antigen and eventually it will not be detectable. However the antibodies would. In the event of not having produced antbdoies for whatever reason, the p24 antigen will always be detectable.
So a normal combo test used in Europe at a modern big hospital would be sufficient?
I talked to a Senior MD at the infectious disease klinic in the university hospital of Malmö (Sweden). He said that if your immunsystem would be somewhat defect it would still be able to produce antiboddies. The antibody testing of today are extremely sensitive and he had not seen any evidence of people not serconverting after 3 months with modern antiboddy testing.
These extreme cases with no seroconversion must be due to old tests, wrong tests ore some extrem weak immunsystem in these people. He hase worked with HIV for 20+ years.And he said he trusted hard evidence and this would not be possible.
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.