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HIV TESTING Doc HHH

i had an unprotected encounter with a csw in pakistan.the next day,i went for elisa test on archtect abbot ab/ag 4gen test to my shock it cameback, borderline reactive 1.15, next day repeated the test in another lab using the same machine(abbot) and reactive 1.35.I changed the lab and went to a hiv refferal labas advised by a doctor,after 7 days in a refferal lab ( NIH ) using vironostika 4 gen ab/ag plus every time they run the elisa,they do aswell on 2 rapid test  Determine and Bioline.1 week= negtive.3 weeks=negtive.5 weeks=neg.i talked and The csw agreed to get tested .she tested negtive on three different labs in (NIH), and one using  ECLIA 4gen cobas 6000 (e601) plus another  reputed lab .BUT SHE DID NOT TEST ON ABBOT(the intrument that gave me postive).Week 8,in anxiety i again changed the lab,i tested from another very good lab (AGHA KHAN) using ECLIA 4gen cobas 6000 (e601) Negtive.Week 10 from (Agha khan) negtive.Week 12 (NIH) negtive.Week 14 from (NIH) negtive.now after reading an incent of a person who was testing negtive on other instrument but testing postive on abbot.i decided to go to another lab with have abbot but not from the one which gave me a postive.abbot week 16,ask for a blood sample twice,due to some boderline problem but gave non reactive result, but high index value 0.83 cutoff 1.0 .Week 18 from NIH negtive,this time i did a Wetern blot along this test,it came negitive aswell,but i was lucky enough to see my test strips.it was clear no bands but there were some black dots very tiny only visible to naked eye( I HAVE A PICTURE). after being tapped into a result book.I would tell about my symptoms bu that would be sepculating the topicbut the for most is pimples res ittch bumbs,i have 5-6 on my chest today.(but is monsoon season here)
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300980 tn?1194929400
MEDICAL PROFESSIONAL
Brief follow-up answers.

1.  The rash of the ARS does not last more than a few days and usually is flat, not pimple-like.  Further when people have the ARS rash, they also have high fevers, muscle aches and feel bad.

2.  The idea of late seroconversion is a falsehood which continues to be promoted on the internet. There is no sceintific evidence that such a thing exists.

3.  Your test results are definitive and show that you do not have HIV.

This will end this thread. There will be no more replies. EWH
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Avatar universal
i totally understand your answer docotor i just want a bit explanation ,as you have a very expert and updated knowledge on these paticular issue.
1)u said u DOUBT my pimples are due to hiv? doctor i have had pimples through out these 6 months,small to a bit small sized to lilttle red elevated/with irraitaion,neck ,back ,arms,face.time to time every where.do u see pimples or red bumps as an ealry ars syptom? Or they are totally ir relevent to finding out hiv ars?
2)u said late seroconversion is a internet myth?pls explain a bit more ? i dont know if i have any auto immune or any other condition that can delay antibody production?even with any such conditon 5 months is enough u know?have u seen any case of late seroconversion in fairll normal healthy people?
3)AND as being an expert ,seeing my test results ,which are totally as i explained(as explaing in person wont explain it any better), will u interpert my first results as 100% sure false?with the seriies of test after that? without know ing the index values?

pls explain a bit.this will be the end of my questions.thankyou
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300980 tn?1194929400
MEDICAL PROFESSIONAL
Your questions are repetitive and my answers are not going to change.  Briefly:

1)firstly doctor i would like you get yor thought about pcr dna qulaitative test.should i go for a pcr to rule of late seroconversion?? will a combo at this time is equally reliable to pcr which detects the virus itself?

You do not need more testing.  PCR testing is a waste of time and money.  

2)have you seen late seroconversions???with these combo over 5and half months?

Late seroconversion is a myth from the internet which does not exist. your tests are defintive.  There is no such thing as late seroconversion.  

3)would you remmond me to do a 26 week combo(6 months) or a pcr at 24 weeks to be a 100% sure?

As I said above, further testing of any sort is a waste of time and money.

4)again my western blot test,i do believe in the labs interpetation,i just want to know that tiny black dots dont really mean any thing?there have to be clear bands visible to make a prensence of antibodys?

I already told you, the dots on your Western Blot have no effect on the accuracy of the test. Believe the results.  

Lastely doc iv seen some negtive results but the cuttoff tend to get higher every time recently i got a negtive at week 22 cuttoff 0.69 and cuttoff 1. had gone up from 0.46 steadily.in your clinic aswell any thign under one would be a clear negtive??

the background levels of negative tests can fluctuate. negative is negative.  Believe you tests.  EWH
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Avatar universal
thanku doctor,u must be knowing copeing with false postive can be stressfull sometimes.
doctor i would like you to comment on these few inquires
1)firstly doctor i would like you get yor thought about pcr dna qulaitative test.should i go for a pcr to rule of late seroconversion?? will a combo at this time is equally reliable to pcr which detects the virus itself?
2)have you seen late seroconversions???with these combo over 5and half months?
3)would you remmond me to do a 26 week combo(6 months) or a pcr at 24 weeks to be a 100% sure?
4)again my western blot test,i do believe in the labs interpetation,i just want to know that tiny black dots dont really mean any thing?there have to be clear bands visible to make a prensence of antibodys?
and lastely doc iv seen some negtive results but the cuttoff tend to get higher every time recently i got a negtive at week 22 cuttoff 0.69 and cuttoff 1. had gone up from 0.46 steadily.in your clinic aswell any thign under one would be a clear negtive??
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL

. Your initial tests were falsely positive.  Please remember that no test for HIV would turn positive one or two days after exposure to an infected partner.  Your subsequent tests, prove that you were not infected.  

1) would u consider me hiv negtive?

Yes.

2)how would you explain my my false boderline postive or the ratios that came near to cuttoff?

They are falsely positive, most likely due to non-specific reaction of something in your blood with something in that particular test.

3)4)A single encounter without ejuc.3-4 sec max.low risk or zero risk?for my girl friend ,Is her symptoms consistent with any std that I have not checked or checked too early for, i have read tonsilitus is consistent with oral std?is it to hiv? could the rash and sore toat be bcz of the medication taken for tonsilitus?

Very low risk but not zero.  Your girlfriend's illness is not related to HIV from your encounter.  

4)my western blot is it denfinative? can u explain any reasons for the black spots?CAN i upload a pic? and should i go for a PCR incase im going through late seroconversion?im a healthy normal 25 year old male?

Yes, your Western Blot, like your other tests, provided definitive results.  Believe the lab's interpretation.

5)and my pimples and red bumbs are they consistent with hiv or any other std?

You do not have HIV.  I doubt that your pimples are due to HIV but I suggest you discuss what is causing them with your doctor.  

Take care. EWH


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Avatar universal
sorry for not following the guidelines doc,i just thiught better explaing would result in better answers thats all.
my questions1) would u consider me hiv negtive?
2)how would you explain my my false boderline postive or the ratios that came near to cuttoff?
3)4)A single encounter without ejuc.3-4 sec max.low risk or zero risk?for my girl friend ,Is her symptoms consistent with any std that I have not checked or checked too early for, i have read tonsilitus is consistent with oral std?is it to hiv? could the rash and sore toat be bcz of the medication taken for tonsilitus?
4)my western blot is it denfinative? can u explain any reasons for the black spots?CAN i upload a pic? and should i go for a PCR incase im going through late seroconversion?im a healthy normal 25 year old male?
5)and my pimples and red bumbs are they consistent with hiv or any other std?
Helpful - 0
300980 tn?1194929400
MEDICAL PROFESSIONAL
Welcome to our Forum.  Dr. Handsfield and I take questions interchangeably depending on availability.  Today you happened to get me.  For your information, Dr. Handsfield and I have worked together for over 30 years and do not differ in opinions, although our writing styles may vary.  

This question will not be answered in its present form however.  you have not followed our guidelines regarding the length of questions and have greatly exceeded the word limit.  Please re-state your question much more briefly and I will address it.  EWH
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Avatar universal
QUESTIONS
1)is my testing conclusive, like 18 weeks and a western blot this time?seeing my situation, would u conclude it as a false postive(abbot one)?100% sure in your advice.
2)The most frequent combo im haveing , vironostika 4 gen ab/ag ,is it a good licensed testing instrument ? i have heard it picks up large amount of antobodys only, like 150 per mml i guess.and does it pick up all subtypes.
3)A)Is the CSW negtive after 6 weeks very encouring towards a definative answer?
3)B)My negtive but close to cutoff again at archietect at week 16 and week 22 at NIH.does it mean any thing?even the third time it was negtive but a close to cutoff????
4)A single encounter without ejuc.3-4 sec max.low risk or zero risk? ,Is her symptoms consistent with any std that I have not checked or checked too early for, i have read tonsilitus is consistent with oral std?is it to hiv? could the rash and sore toat be bcz of the medication taken for tonsilitus?
5)The black spots I saw on western blot do they mean the same as bands or its just some simple contamination?(PLEASE TELL ME IF THERES ANY WAY I CAN UPLOAD PICTURES BCZ I WOOULD LIKE SO SHARE SOME.
6)HOW much clearer picture will PCR GIVE? Im really going nuts over pcr.like is it also good after so many days.NOW I THINK ONLY THIS TEST WOULD GIVE A RELIABLE ANSWER???
7)My pimple kind of things don’t stop comeing?is this an indication of any other std ?got 7-8 over chest and belly today?
8)Most horrifing fact.late seroconversion?would 22 week testing rule out late seroconversion with the latest combo?doctors state this does happen today aswell?.
i know i have asked alot hope you could help me, i had to post comments to fully explain my self i apologize  but i had to ask all there was in my mind thank you
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Avatar universal
The thing that gave me more panic was some conditions with my g.f ,about 2 months from this encouter im telling about, she gave me a breif oral(2-3sec max), without educlation(the only encounter in this time).she got follicular tonsilitus like after 3 weeks or so for a week,and very strong(she had to inject antibiotecs but become better in a week..two weeks later rash on her both arms ,was there two days went after medication anti biotecs( I HAVE A PICTURE). and fever for just one day,one week later dry cough for allmost two weeks,on and off since then.i havent told her im testing.WEEK 22 negitive from NIH but this time again high index.0.134 cutoff 0.196. i also checked for hep b, c herpes 1 and 2(iGg 1 and iGg2) and spyhilis(VDRL and TPHA).negtive allmost 8 weeks past exposure.
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