hi
I am getting the result of my 7 week test in a few hours. I am really nervous. Someone on here said that at 8 weeks, no one has seen an 8 week negative change to a positive at 12 weeks. I was wondering if that is still true and how can anyone test positive at the 9-12 week mark then if they would test negative at 8? I think an 8 week result is about 97% accurate isnt it? so would that mean a 7 week would be about 96% accurate for most people? It's just I read pn here some one saying that some peoploe think an 8 weeker is conclusive for the vast majority of people and only a very small minority need to test at 12 weeks. thanks./ God I am so nervous.
I have had 3 different timings for primary hiv symptoms during my time at the clinic. On here people and the Drs say 2-4 weeks, a health adviser at the GUM clinic said 4-6 weeks and yesterday after my test another health adviser at the same clinic said 6-8 weeks.
Really confusing or what. Maybe it could happen anytime up to the 12 week window period, no?
The thing is symptoms are never a good indicator, EVER! So people need to stop thinking about symptoms and relating them to HIV because the correlation is not really there. Many infected people are completely asymptomatic. And if symptoms are showing up, they mimic those found in a million things that are MUCH MUCH more common so most likely the symptoms are related to that (if not for the anxiety the person is experiencing).
HIV 1 and 2 antibodies and p24 antigen test (HIV DUO or HIV Combi test)
This HIV test is licensed in the EU for use after 28 days after a possible exposure. It is probably much better than this and will probably identify the majority of newly infected HIV positive individuals at between 14 and 21 days. This HIV test is referred to as a fourth generation HIV test. Certainly in our clinic we have had many new diagnoses of patients using this HIV DUO test combination in that time frame.
The HIV DUO test relies on the principle that when HIV first establishes itself in the body it will start to replicate rapidly and almost as a by-product of this replication a core protein - the HIV p24 antigen - is produced in huge amounts from around 10 days or so after first infection and before or during the time when antibodies to HIV are being formed. The p24 antigen will then stay at a very high level for the first few months after infection and later decline in line with the decline in HIV viral load as referred to above. It will though never completely disappear and will run a variable course of detection through the rest of the illness.
So in general, p24 antigen is formed slightly before antibodies are forming allowing us to close the gap between infection to detection time - the HIV window period. As time goes on, then the majority of newly infected HIV positive people will form antibodies to HIV 1 or 2 by 28 days. In combination then, looking for both the HIV 1 p24 antigen and also HIV 1 and 2 antibodies will allow for much earlier detection of HIV than looking for HIV antibodies alone.
Fully conclusive at 28 days onwards... 99.98% accurate mate this is fact....this goes up with everyday later you test...
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Current methods for the detection of HIV may not detect all infected individuals. An ARCHITECT HIV Ag/Ab Combo test result that is nonreactive does not exclude the possibility of exposure to or infection with HIV-1 and/or HIV-2. Nonreactive results in this assay for individuals with prior exposure to HIV-1 and/or HIV-2 may be due to antigen and antibody levels below the limit of detection of this assay.
UK testing guidelines.
Post-test discussion
The need for a repeat HIV test if still within the window period after a specific exposure should be discussed. Although fourth generation tests shorten the time from exposure to seroconversion a repeat test at three months is still recommended to definitively exclude HIV infection.