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Can Abbott Architect HIV 1 and 2 ag/ab combo give a false negative afte...
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Can Abbott Architect HIV 1 and 2 ag/ab combo give a false negative after 3 months

I tested at 3 months and 5 days post exposure with Abbott Architect HIV 1 and 2 ag/ab combo with a negative results. Before I was tested with Abbott HIV 1/2 antibody rapid blood test at 8 week and 3 months period which were also negative.

Now I have read in aidsmap that it may be sometime possible for 4th generation test that p24 antigen will decline undetectable while antibody still not detectable. So here caught anxiety for this gap that may be I tested duo in seroconverting during 3 months and 5 days. Kindly anyone answer my below question...

1. Is it possible I am seroconverting at 3 months and 4 days and p24 antigen decline and antibodies also not at the detectable level?

2. Can Abbott Architect HIV 1 and 2 ag/ab combo sensitive enough to pick even a very small amount of antigen or antibody at seroconverting period.

3. How many total documented cases are available of seroconverting after 3 months.
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5628687_tn?1371411467
a highly sensitive test.HIV tests are amongst the best tests in the world nowadays.even in recent years the sensitivity of testing has improved dramatically.you do not have HIV.personally if your anxiety heightens i would recommend a combination of therapy and maybe temporary medication.i am a sufferer of acute anxiety disorder(generic rather than HIV based).i was prescribed 75mg dosulepin daily with cbt.the meds take the edge off and the therapy teaches you to work through the anxiety long term. works for me
16 Comments Post a Comment
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5628687_tn?1371411467
you have conclusively tested negative.searching the internet for horror stories is feeding your anxiety.many say that 3 months is to late to pick up the p24 antigen but you do not have to worry as you were screened for antibodies at 3 months.modern tests are highly sensitive and you are well and truely HIV negative
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Avatar_m_tn
Thanks for your reply.

But I dont know how to overcome on my hypochondria which has totally ruined my life.

I am still thinking I may be screened in the time where neither p24 antigen nor antibodies are detected.

Can anybody say me about the sensitivity of  Abbott Architect HIV 1 and 2 ag/ab combo. Will it leave not to pick the small amount of p24 or antibody?
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366749_tn?1370585676
Trust your results. Your test is conclusive and you do not have HIV
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5628687_tn?1371411467
a highly sensitive test.HIV tests are amongst the best tests in the world nowadays.even in recent years the sensitivity of testing has improved dramatically.you do not have HIV.personally if your anxiety heightens i would recommend a combination of therapy and maybe temporary medication.i am a sufferer of acute anxiety disorder(generic rather than HIV based).i was prescribed 75mg dosulepin daily with cbt.the meds take the edge off and the therapy teaches you to work through the anxiety long term. works for me
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Avatar_m_tn
Thank you dear. I have started to focus on other things and I am feeling now a bit ok. Here in the Philippine some Doctors are still advising on 6 months which was given in the AID Act in 1998. What I was doubting that may be I am in the conversation and and there is a gap in which neither antibody nor antigens are detected in my test at 3 months five days.

Whenever my infant baby feel any flu so I become again paranoid.
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Avatar_m_tn
Above words have a small mistake.

I mean seroconversion.... Not conversion
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173692_tn?1371540094

http://www.cdc.gov/globalaids/Resources/pmtct-care/docs/TM/Module_6TM.pdf
Page 11
#4
  In an adult, a positive HIV antibody test result means that the person is infected, a person with a negative or inconclusive result may be in the “window for 4 to 6 weeks but occasionally up to 3 months after HIV exposure. Persons at high risk who initially test negative should be retested 3 months after exposure to confirm results
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480448_tn?1397235344
Seek help for the anxiety!
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Avatar_m_tn
Thanks Teak. Very good info.


Can you please tell me specifically about the Screening test by Abbot Architect combo ag/ab and its window period. I mean is its sensitivity of picking even a small amount of ag and ab.
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5628687_tn?1371411467
i believe the standard sensitivity is around 50 copies per ml,that is highly sensitive,alot of literature on the internet is not factual or accurate.even some very well respected sites post out of date information
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5628687_tn?1371411467
check out the journal entry which nursegirl wrote.it explains about modern testing and the myths around testing , it really is worthy of being on the forum itself but rules are rules so take a look
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Avatar_m_tn
Can you please copy the links for me for that journal.
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580755_tn?1357673215
Why not click on nursegirls name and look at the journal yourself?
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5628687_tn?1371411467
i may get into trouble for this but ive copied and pasted a segment from the journal.hope u dont mind @ nursegirl .....


First of all, sadly, there is a very overlinflated view of HIV among a large portion of the general population.  I feel this is related to a lot of the "hype" and media around the virus.  The FACT is, HIV is a very difficult virus to transmit.  Comparable to other viruses (ie influenza), it is a very WEAK and unstable virus that succombs to the environment rapidly.  It needs basically a set of near perfect circumstances to allow for infection.  Therefore, a person CANNOT get HIV from environmental surfaces, like toilet seats, manicure/barber equipment, shower stalls, drinking glasses, toothbrushes, etc etc.  The virus quickly becomes inactive when it is outside of its host (the body).  This is why infection from inanimate objects is impossible.  This is also why mutual masturbation with exposure to a partner's gential (genital) fluids is also NOT a risk in any way.  This also is the case with cuts, abrasions, cracked cuticles, etc.  Those things make no difference when it comes to risk, as the virus is outside of its host, rendering it inactive.

"Delayed Seroconversion".  We have all heard horror stories of people who test negative for YEARS, even decades, somehow being infected without having a POS HIV test.  This is a bunch of "you know what".  It doesn't happen, it is an urban myth.  If a person has transmitted the virus, they will test pos, actually quite rapidly (usually within 6 weeks of exposure).  3 months will give a person with an exposure a conclusive result.  If a person does not test POS for HIV 3 months after an exposure, then they did not contract HIV.  The ONLY exception to this is people who have literally NO immune system who may take longer to produce antibodies.  This would include an extremely small portion of the population, and would include situations such as....a person taking anti-rejection meds post an organ transplant, a person on aggressive chemotherapy, or a person with terminal, end stage cancer, again...people who have NO immunity.  Even this "delayed" seroconversion among this small population is highly debated among medical professionals.  Even people in these categories usually test POS within the 3 month window period, but as a precaution, it is recommended that people with severely compromised immune systems test to 6 months post an exposure.  NO ONE ELSE NEEDS TO TEST BEYOND 3 MONTHS.  If a person was prescribed PEP ("Post Exposure Prophylaxis), then they need to test 3 months after their LAST dose of PEP.

"Autoimmune Disorders".   This is often confused with what I discussed above.  Autoimmune disorders (ie rheumatoid arthritis) are completely different from a person with a severely compromised immune system, from chemo, etc.  The presence of an autoimmune disorder does NOT change the testing guidelines whatsoever, and it will not affect the test results.
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707563_tn?1395081210
This thread is closed. Your questions have been answered again and again.

Thanks,

Emily

                                 ******** CLOSED THREAD ************
                                    NO MORE POSTS, PLEASE
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Avatar_m_tn
Thanks to All who posted here the very resourceful information. This thread will be really informative for all who are suffering from sever anxiety like me. Thanks Emily for concluding this thread to end. I respect the forum rules and I will be here to answer and help other persons like me.

Best Wishes & Stay Blessed.
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