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Confused about the TYPES OF TESTS & GENERATIONS
by kpelych19602, Apr 19, 2009 12:16AM
I understand that an ELISA test looks for antibodies. I am from the United States. Does the GENERATION of test matter as to sensitivity? I know a lot of sites say 6 weeks may be accurate, but would that be with a earlier generation test, or are they talking about newer generations? (Although I do realize that 12 weeks is conclusive no matter what). For example, is a generation 3 test a combo ag/ab test? Or are there generation 3 tests that strictly look for antibodies? That is what I am confused about. Are generation 3 and 4 tests generally used in the USA? Also, what is the difference between a PCR DNA test and a combo ag/ab test? Sorry for so many questions but I just want to be informed on the newer tests.....I have tried to read as much as I can about them on here and other websites first, but I am really only familiar with the original ELISA tests.....thank you!
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to my shock, my icma came back repeated reactive {2.43} with neg. pcr.
and neg. western blot.I retested with quest with an eia., not sure which generation, but it was non-reactive at 8 weeks with neg pcr. i have autoimmune of graves with autoantibodies to hashimotos. Do you think the icma picked up something the eia missed or a false positive with icma? I know you are not a doctor, but I value your opinion, although I don't like your opinion about pcr. Will an antibody test at 12 weeks be conclusive if I use the eia from quest or do you recommend the icma from lab corp. Do you think 12 weeks is adequate for a conclusive result or must I wait 13 weeks?
thank-you in advance for your time
-JC-
-JC-