HIV PREVENTION COMMUNITY
Sensitivity

Sensitivity

Information provided to me from one of the labs in the UK that provide HIV testing to the majority of private doctors on Harley Street, London. Hope it helps someone;

   Specific tests for HIV include antibody and antigen (p24); Screening serology
is done by ELISA. Positive specimens are then confirmed by a different method
(e.g.. Western blot).

  50% of ELISA tests are positive within 22 days after HIV transmission; 95% are
positive within 6 weeks after transmission.
The sensitivity of screening serological tests is ~99.5%. Molecular biology
techniques (PCR) show a small incidence of individuals (<1%) who are infected
with HIV for up to 3 months without generating antibody response.
  The specificity of positive results by two different techniques approaches
100% even in low risk populations. False-positive screen tests may occur as
normal biological variants or in association with recent influenza vaccination
or other disease states such as connective tissue disease. To avoid
false-positive results, repeatedly reactive results must be confirmed with
Western blot assay. False-positive screening tests are usually detected by
negative confirmatory tests.
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2 Comments Post a Comment
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Avatar_m_tn
Great info, from a reliable source also.
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Avatar_n_tn
Good info!  I will refer to this often when any other forum users have questions on this and will refer them to this thread or copy-paste it for them.   and I hope you get over your mental anguish about not being positive!  Thanks!

-WorriedUS
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