late seroconversion

I had a brief receptive anal episode(without ejaculation) and I already got "negative result" from FDA approved test (Oraquick Advanced)

but now I worry about late seroconversion regard to other food or medicine

I have read the paper that Korea Red Ginseng(KRG) can suppress HIV.
http://www.thebody.com/content/art30196.html

And some HIV gene can be destroyed with KRG (the report refers to this is written in Korean and japanese so that it cannot be read by you, english users. So, I will not write here)


Is it possible taking a KRG for about 1 month can make a similar effect like PEP, so that late seroconversion occur?
Or, there is no effect on test result?

I absolutely need your help!

[ricky_id]

Supress doesn't mean eliminate.

Was the anal sex with condom, and if yes, did it break? How long post-exposure did you test?

[consularkor]

of course unprotected anal sex makes me nervous, and 3 month negative test result mark is already done.

But, if KRG suppress HIV, It will proliferate slowly.
late seroconversion is  possible?

[Teak]

After reading about KRG. It would not suppress antibody production. What the on going study is about is the correlation of KRG and the suppression of CD4 destruction..

[consularkor]

I really appreciate for your help, Teak. I have some more questions.

1) This is the report professor Cho in Seoul Asan Hospital.

Twenty hemophiliacs were infected with Korean subclade B (KSB) of HIV-1 from two cash-paid plasma donors in Korea in 1990. Our previous studies revealed that Korean red ginseng (KRG) intake increases the frequency of gross deletion in the nef gene (gDeltanef). We investigated whether KRG and highly active antiretroviral therapy (HAART) affected the frequency of gDeltanef in the 20 hemophiliacs who share common characteristics of the HIV-1 source, mode of transmission, and infection time. Over a 10-year period, we obtained 522 nef amplicons by nested PCR using 172 samples of peripheral blood mononuclear cells. Of the 522 nef amplicons, 69 (13.2%) were gDeltanef. Despite a 2-fold higher monthly dose of KRG, the frequency of gDeltanef detection (3.2%) was significantly reduced during HAART compared with that prior to HAART (20.6%) (p < 0.001). gDeltanef was detected significantly more in patients treated with a monthly KRG intake of more than 60 g (26.8%) than in patients treated with a monthly KRG intake of less than 60 g (10.5%) (p < 0.05). These finding suggest that the frequency of gDeltanef is dependent on the amount of KRG intake, although further study is needed. These data might provide a new perspective on the pathogenesis of HIV-1.

If this report is true, some genes is destroyed by KRG. So late seroconversion would be possible?


If you answers this, I would not post anymore.

[consularkor]

2) another report is here

To investigate the association between Korean red ginseng (KRG) intake in HIV-1 infected patients and the occurrence of grossly deleted nef genes (gDeltanef), we characterized nef genes in 10 long-term slow progressors (LTSP) infected with HIV-1 subtype B and 34 control patients. LTSP was defined by the annual decrease in CD4 T cells being less than 20/microl over 10 years in the absence of antiretroviral therapy. They were treated with KRG for a prolonged period. Nef genes were amplified from peripheral blood mononuclear cells (PBMC) using nested PCR and the products were sequenced directly. It was observed that the patients CD4 T cell counts decreased from 444 +/- 207/microl to 294 +/- 177/microl over 136 +/- 23 months of KRG intake. This corresponds to an annual decrease in the level of CD4 T cells of 13.3/microl. A total of 479 nef genes were amplified from 137 PBMC samples. Nine out of the 10 patients, 47 (34.3%) out of the 137 samples, and 90 out of the 479 genes revealed gDeltanef. The deletion extended outside the nef gene in 25 gDeltanef obtained from 6 patients. The proportion of samples with gDeltanef (34.3%) was significantly higher than 4.8% in control patients (P < 0.001). In addition, it significantly increased as the duration of KRG intake prolongs (P < 0.01). These data suggest that the occurrence of gDeltanef might be associated with long-term intake of KRG.

[Teak]

It would not delay antibody production or delay seroconversion.

[consularkor]

Thank you for your advice.