That's a good question that i don't know the answer to, but i will say that there are several factors that i do know can cause weight loss to occur. The first of them is that those in the primary
infection. I've also read reports that also mention the route of transmission may play a major role in determining this-some say those infected via a needles are more prone to experience recurring muscle wasting / weight loss. It's also thought that the disease may have certain built in programs it activates as it progresses that act as a template through out the course of the sufferers illness trigger these.