Aorta valve stenosis when severe restricts the amount of blood pumped into circulation with each heartbeat. The valve opening is smaller than normal and can be caused by calcification. With less blood pumped into circulation with each heartbeat the heart needs to work harder to meet the oxygen/blood demand.
The overworked heart will cause the left ventricle to enlarge and the enlargement reduces the contractility (weak pumping) of the left ventricle causing heart failure. Heart failure indicates less blood is pumped into circulation than is received from the lungs, and blood backs up into the lungs causing fluids to leak into the lung tissues. This causes congested (lung edema) heart failure.
Six years ago I was in ICU for congested heart failure, and the treatment was to stablize the oxygen level to 95%, and medication to reduce the heart's workload, etc. With kidney failure, etc. your sister's condition is more advanced than my prior condition. A surgeon wouldn't want to risk your sister's life with an operation. CHF patients are at a very high risk for an operation...if the symptoms can be successfully treated especially an increase
to the pumping of blood out of the left ventricle.