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Dear Rich, thank you for your question. With an angioplasty/stent procedure that has no in-hospital complications, the risk of subacute stent thrombosis over 1-2 weeks after the procedure is < 1% with aspirin and plavix therapy. After 2 weeks, the stent begins to endothelialize which means that cells coat the inside lining of the stent eliminating the risk of thrombosis. Restenosis within a stent is caused by proliferation of the intimal cells which line the inside wall of the artery. This process occurs in approximately 15% of patients and is usually identified by a recurrence of angina or the presence of ischemia on a stress test. Routine stress tests after a stent procedure are not recommended but many cardiologists prefer to perform such a test 3-6 months after the procedure to ensure that restenosis hasn't occurred. Many different therapies have been tested to prevent restensosis, but there are no medications that you could take that have been shown to be effective. However, to prevent the progression of atherosclerosis in areas other than the stented segment, you should exercise daily, eat a low-fat and low-cholesterol diet, and avoid tobacco.
I hope you find this information useful. Information provided in the heart forum is for general purposes only. Only your physician can provide specific diagnoses and therapies. Please feel free to write back with additional questions. Good luck.
If you would like to make an appointment at the Cleveland Clinic Heart Center, please call 1-800-CCF-CARE or inquire online by using the Heart Center website at www.ccf.org/heartcenter. The Heart Center website contains a directory of the cardiology staff that can be used to select the physician best suited to address your cardiac problem.