Amiodarone, Tremors, and Loss of Appetite

Posted By Bruce on July 04, 1998 at 21:50:06:







The Patient:
72 year old male, my father.
A brief history:
April 27, 1998 - My father experience a heart attack.  No prior symptoms, but had been living with Atrial fibrulation for 2 years.  Drugs in use - Rhythmol, Varapamil. (Not sure about spelling)
April 28, 1998 - Emergency triple bypass surgery. Hypoxia suffered.
May 18, 1998 - Staff infection in chest made second surgery necessary. Debreding was performed.  Many days spent in ICU.  While on ventilator, experienced something called encephalopathy.
While in Rehab it was determined that he is now experiencing BradyTachy syndrome, i.e. the drug used to prevent atrial flutter slows the heart down to much, and drugs to stimulate cardiac output speed it up too much (?).  A pace maker was recommended.  Loss of appetite noted during this time.
June 23, 1998 - Drugs stopped in preparation for surgery.  Significant recovery of appetite experienced. I was amazed!  
June 24, 1998 - Pacemaker was inserted. (Medtronic Kappa 400).  He asked for food immediately after the procedure!
June 25, 1998 - Pigtail lead came loose and a second procedure was performed to reconnect in the heart.  Again still eating well, and asked for a candy bar after surgery!
June 27, 1998 - Back to Rehab. He is currently better but a loss of appetite has returned.  In addition, he has tremors and fatiques easily.  In order to get out of the hospital he must get stronger.  In order to get stronger, he must eat.  He won't eat, can't eat, doesn't know why, and is very depressed.  NOW THE ASUMPTIONS AND QUESTIONS:
Based on this history I believe this is strictly drug related.  I am not a physician, just a worried son.  He is on Amiodarone and Lotensin. Are these drugs responsible for his fatigue, tremors and loss of appetite?  And, if so, what can be done to get out of this vicious cycle?  Are there other choices?
Sincerely,
Bruce and a concerned family.