In lay terms can you tell me what asymetric septal hypertrophy is, how it is treated and what the prognosis is. My sister, a 54 year old, has just been diagnosed with ASH and has been given little information. She has mild aortic and mitral regurgitation as well. I had an aortic valve replacement (11 years) with a allograph (presently have a +2 leakage) which was diagnosed as a congenital defect. Are these conditions related and could they have been caused by alcohol during pregnancy? Our mother had alcoholic cardiomyopathy. I also have a brother (62 years of age) who has a heart murmur but no other apparent heart problems however, he has had surgery for and is now on disability because of cerebral aneurysms (3) - 2 of which were corrected with the 3rd inoperable. Makes me wonder if all of these conditions are due related in that we had an alcoholic mother.