Hello,
Celebrex can raise blood pressure. The only way to know for sure is to stop taking it and check you blood pressure for a few weeks afterwards. There is no relationshop that I know of between statins and blood pressure. I am sure you already know this, but the best solution for knee pain and hypertension is to lose hte extra 50 lbs. If your blood pressue stays elevated, you should probably start and antihypertensive medications until you weight is under control -- either a diuretic like hydrochlorothiazide or an ACE inhibitor.
I hope this answers your questions. Thanks for posting.
Sorry for the confusion.
Jon