It can cause all of those symptoms, however, depending on your risk profile for coronary artery disease, your doctor may lean more towards ruling out CAD. Having a normal echo, ekg and stress test is very reassuring. Also, the fact that your symptoms return when you are off the PPI is also suggestive that GERD is the likely etiology of your symptoms. Unfortunately, taking a PPI, such as prilosec, is not the answer to treating GERD. GERD is typically associated with poor lower esophageal sphincter tone which is related to a bad diet rich in fats, cholesterol, alcohol or caffeine, a lack of exercise which may lead to obesity and poor sleeping habits.