I had and MI, or possibly acute cardiomyopathy) 1 year ago. I have been told both at different time. LVEF was 45% 2 months after. This was first assessment.. due for another soon. I am on 6.25 mg carvedilol twice a day. I am not physically restricted - I walk 1 mile or more day and do 10 minutes of other light exercises most days. My BP runs under 120/80 most of the time. I understand carvedilol helps prevent stiffening of the heart muscle and can help restore LV function to some degree. How specially, so it do this? What is the biochemical mechanism?
Carvedilol belongs to a class of drugs called beta blockers. It is responsible for inhibition of beta receptors present ubiquitously on the heart muscle. By blocking these receptors, it helps prevent the effects of adrenaline/noradrenaline on the heart thereby maintaining a low heart rate and reducing the energy expended by the heart per beat.
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