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Coumadin, Plavix, and Tylenol
My grandmother was in the hospital last weekend with an INR of 9.2.  I had later found out that her doctors had told her it was OK to take extra strengh Tylenol in addition to taking Coumadin and Plavix.  Is this OK?  In addition, what is the purpose of taking both Coumadin and Plavix?  I understand they work by completely different mechanisms, but is taking both necessary?  I am concerned she is not getting the correct information from her doctors.  Also, I did my dissertation research in coagulation, so I can understand very technical answers.

Thank you, Dr. Melisa Barhoover
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I can't believe there IS an INR of 9.2.  Don't they check her INR?  That has got to be dangerous; ordinarily, one shouldn't go much above 3.5.

It sounds like maybe she hasn't switch to home INR testing--I know people who just don't get around to going to their "monthly" check for three or four months, and don't really appreciate the risk they are taking.

If she doesn't want to mess with home testing, her caretaker or family member could learn and do it fairly readily, I would think.

Just curiosity--where did you do your grad work?  Is there a ton of anti-coagulation research going on?  (I'd think so, since it seems to be far from an exact science at this point.)
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Thanks.  I do not think my grandma does home INR testing.  My grad professor could not beleive  the INR either, it really is amazing that she is alive.

I did my grad work at CSU under Dr. Michael Kalafatis.  

Do you think it is OK to take Extra Strength Tylenol and baby aspirin with the Coumadin and Plavix she is on.  I told her to stop taking it for now because of her dangerous INR level.  The problem with her doctors is that they do not communicate with each other, so her heart specialist is telling her to do one thing, and her other doctor is telling her something different.
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My wife had a INR level taken at the hospital in Liberty Missouri on 6/25/2011. The doctor sent her home from the emergency room with no work for 5 days and to stay in bed.
  As I also take coumadin this is hard to believe when her whole body is aching .
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