Changes in blood volume is not handled the same in a normal versus diseased heart. Normal hearts tend to take changes in blood volume very well, whereas the contrary is not ture.
1. valvular regurgitation?
Decreased blood volume, decreased blood pressure tends to decrease regurgitation. It is common to take someone to the operating room for severe mitral regurg and find moderate MR after sedation (decreased blood pressure decreases MR). Increased blood pressure and increased blood volume increase MR. An acute exacerbation of heart failure is likely to find increased regurgitant fractions because of the increased heart pressures.
2. dimensions of heart chambers?
This is not that affected by volume changes.
3. ejection fractions
A normal heart will have increased ejection fraction with hypovolemia. The ejection fraction would stay the same with hypervolemia.
A cardiomyopathy my have decreased heart function with hypervolemia and may also have an increased ejection fraction with hypovolemia.
Take this with a grain of salt because the curves for pressure volume loops break down with too much or too little preload. do a google image search for Frank Starling mechanism or Frank Starling curve.
In a normal heart there is little effect on pulmonary pressures. Pulmonary pressures in a cardiomyopathy or with valvular disease can increas substantially with hypervolemia. On the echo this is reported as right ventricular systolic pressure (RVSP).
5. aortic root size / size of aorta
blood volume should have no effect on these measures.
I hope this helps. Good luck and thanks for posting.
Copyright 1994-2017MedHelp International.All rights reserved. MedHelp is a division of Aptus Health.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.