HEART DISEASE COMMUNITY
Healthy vein or artery

Healthy vein or artery

Is it possible to transplant a healthy artery from one person to replace a damaged artery in another person?
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976897_tn?1317787410
Yes, but there are some very good synthetic arteries which should be available in the near future. They don't block, and they have elastic properties which allow them to pulsate like normal vessels. Of course, the only thing they lack is the ability to alter the area of the lumen.
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367994_tn?1304957193
If a heart transplant can be accomplished, It seems it isn't any leap to apply the arteries as well. Patency of the vessel may be an issue, and I don't know of any treatment to clear the vessels.

I doubt there can ever be synthetic arteries as there is a requirement for the vessel to interact at the cell level to sympathic and parasympathic nerve impulses. I doubt any technical feasibility possible.  That would require artifical endothelium cells (that line the vessel wall) that monitor blood flow and send signals to the brain to dilate or constrict to help maintain a balance of blood flow between the left and right side of the heart. Also, when the cardiac output is decreased the endothelium cells interface with the nerve impulses that spike the kidneys to increase volume, etc, etc.  A porcine vessel sounds reasonal and resources should go to that possibility...I understand their anatomy is similar to humans.  Also, stem cell therapy may be another option.  Interesting question.  
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976897_tn?1317787410
"I doubt there can ever be synthetic arteries as there is a requirement for the vessel to interact at the cell level to sympathic and parasympathic nerve impulses."

Scientists obviously disagree...   http://news.bbc.co.uk/1/hi/8435879.stm

I'm totally lost with what you mean with nerve impulses being a problem? When a bypass graft is applied to a heart, the idea of the graft is to just get a feed into the native artery, which can then do the rest as it usually would. But the bottom line is, this technology will save lots of lives so it has to be a good thing.
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