Hi Jerry,
1. The Framingham risk predictor is still a very good tool. Other tools can be used to help predict future risk as well, but that doesn’t take away from the Framingham data.
2. That is a very tough question but I have been asked similar questions before. People usually do no like my answer. Modifiable risk factors are modifiable and should be approached as such. Many people view risk factors as an ala care’ menu: I will stop b-d but will continue a and e. If you are really at risk (or in my mind, everyone) you should maximize all risk factor modification through aggressive medical and behavioral changes. Besides, many of these risk factors are inter-related. Obesity worsens hypertension and diabetes. Exercise helps people lose weight, control diabetes, and hypertension. Smoking makes it more difficult to exercise and breath.
The key is living a heart healthy life. No smoking, watch your diet and exercise. These three will help the hypertension, lipids, and diabetes. What ever cannot be managed with diet and exercise should be treated aggressively with medications.
To me, ranking modifiable risk factors is like ranking the answer to a math question: is 1+1 a: 4, b: 5, c: 11. The right answer was not among the choices. It is actually a combination of all of the choices 11-4-5 = 2.
I hope this helps.
Click on "Heart" on the left side of the screen
Scroll down to "Tool: Heart Disease Risk Calculator"
Let me know if that doesn't work for you and I'll get the direct link. Good luck!!
Best thing to do is a Google search with the words "heart risk calculator", and you'll come up with several different links.
Risk factor
Odds ratio adjusted for age, sex, and smoking (99% CI)
Odds ratio adjusted for all (99% CI)
ApoB/ApoA-1 (fifth quintile compared with first)
3.87 (3.39-4.42)
3.25 (2.81-3.76)
Current smoking
2.95 (2.72-3.20)
2.87 (2.58-3.19)
Diabetes
3.08 (2.77-3.42)
2.37 (2.07-2.71)
Hypertension
2.48 (2.30-2.68)
1.91 (1.74-2.10)
Abdominal obesity
2.22 (2.03-2.42)
1.62 (1.45-1.80)
Psychosocial
2.51 (2.15-2.93)
2.67 (2.21-3.22)
Vegetable and fruits daily
0.70 (0.64-0.77)
0.70 (0.62-0.79)
Exercise
0.72 (0.65-0.79)
0.86 (0.76-0.97)
Alcohol intake
0.79 (0.73-0.86)
0.91 (0.82-1.02)
All combined
129.2 (90.2-185.0)
129.2 (90.2-185.0)