High Diastolic Rate

I have metabolic syndrome and most of the aspects of it are under reasonable control with meds except my BP. The Toprol that I'm on keeps my heart rate low, generally in the 60s even when my BP spikes. I monitor it throughout the day with cuffs that are properly calibrated. I find that when my BP spikes my Diastolic can hover around 100 while my Systolic can be in the 130s-140s. My doc would like to have me on Ramapril but I'm on Allopurinol for Gout which could have a bad interaction. Anyway, what are the implications of a Diastolic that is higher relative to the Systolic?

[Cleveland Clinic]

High diastolic blood pressure has been linked to stroke.  I would be very aggressive with your blood pressure control.  You should probably try the ramipril or an alternative ace inhibitor and have your kidney function monitored to look for problems.  You could also consider being on an ARB or a diuteric.  

[Uboat]

What's frustrating is that my BP is typically around 135/84. But at times it spikes really high. In January I was 255 lbs. and now I'm down to 239 on my way to an even 200, based on hydrostatic BMI testing. I'm hoping that will resolve that and other issues.