The information available says one should be instructed not to discontinue therapy without consulting their physician because sudden stopping has, in some cases, resulted in symptoms such as nervousness, agitation, headache, and confusion accompanied or followed by a rapid rise in blood pressure and elevated catecholamine concentrations in the plasma. "When discontinuing therapy with Clonidine Transdermal System, the physician should reduce the dose gradually over 2 to 4 days to avoid withdrawal symptomatology".
Hope this helps, and thanks for your question. Take care,
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