I was previously on 12.5 mg of Coreg 2X a day for high blood pressure. I am also taking 10mg of Lexapro a day for anxiety. This caused me to become very fatigued and my doctor attributed it to the Coreg so he switched me to 10mg Norvasc every day (after weaning off the Coreg for 3 days). This was 2 weeks ago and I'm still feeling the same fatigue. How long does Coreg stay in your system after you stop taking it? I know that Lexapro can cause tiredness as well, but my doctor seemed to think otherwise.