joeblow,
Thank you for the interesting questions.
The answer to your first question is: "it depends". I think that a mid-LAD occlusion with D1 and D2 blockages could most often be considered as a prox-LAD-equivalent lesion. The one caveat would be the size and location of the septal perforators. If a person had a large septal perforator system that arose prior to the mid-LAD lesion, then I do not think the mid-LAD + D1 & D2 blockages would be equivalent to a prox-LAD lesion.
The key factors in deciding on bypass are (1) mortality benefit and (2) quality of life benefit. For a FIRST time operation, most cardiologists agree that the following lesions derive mortality benefit in patients with stable angina:
1. Left main (LM) significant obstruction
2. LM equivalent: prox LAD and prox circumflex
3. 3 vessel disease and low ejection fraction
4. 2 vessel disease with prox LAD stenosis and either low Ef or ischemia on noninvasive testing
5. 1 OR 2 vessel disease with high-risk criteria on non-invasive testing
6. prox LAD lesion with low EF or ischemia on noninvasive testing
7. 1 or 2 vessel disease withlow EF or ischemia on noninvasive testing
For a redo operation, the two basic indications for bypass are disabling angina or bypassable vessels with a large area of ischemia on noninvasive testing.
Many other factors need to be considered prior to deciding on CABG, including age of the patient, their symptoms, their overall health, their expectations, etc. The bottom-line is that you need consultation with an experienced cardiologist to help you sort through the data.
Hope that helps, and Good luck.
Thank you,
Tonyc