Heart Disease Community
LDL
About This Community:

This patient support community is for discussions relating to angina, angioplasty, arrhythmia, bypass surgery, cardiomyopathy, coronary artery disease, defibrillator, heart attack, heart disease, mitral valve, pacemaker, PAD, stenosis, and stress tests.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

LDL

My understanding is that the statins with the greatest LDL reducing effect are Crestor, Lipitor, Zocor, and Pravachol, in that order.  I don’t mention Leschol and Mevacor since they appear to be rarely used since recently due to the aforementioned being more powerful.  Do we have any available solid data on the effects of the various individual statins other than LDL reduction?  For example, do we know which ones raise HDL the most?  What about effects on particle size or Lp(a), etc.  I guess really the most important question would be – is any one of these statins more proven than the rest in regards to reducing cardiovascular events?
Related Discussions
3 Comments Post a Comment
Blank
976897_tn?1379171202
I think it's more of which one your body will tolerate the best. Different brands seem to show different side effects in many people. Lipitor in some women have produced breast pains or enlargement and even the manufacturers cannot explain that one. Still, I suppose it's cheaper than plastic surgery. Some statins cause abdominal pains in some people, or nausea or serious muscle cramps and even damage. So I don't think it's just picking the one which you feel has the best affects, it's which one suits your body the best. In most cases I've read about, statins have hardly affected HDL levels, in fact most people have trouble raising them. When statins lower LDL, this automatically makes the HDL a higher proportion than it was. Triglycerides can also be a problem in some people, trying to lower them.
Blank
159619_tn?1318997813
There are all kinds of statins out there, as ed said, you have to find out which one you tolerate. I have been on them for many years as I was unable to lower my LDL with diet and exercise alone. They have worked well and I have had no side effects, but everyone is different. Most of these can be replaced by the generic Simvastatin. It's cheap and is the basis of many of the meds out there. For instance, it's the generic for Zocor plus Vytorin is Simvastatin with Zetia, a Fenofibrate for lowering tri's.

Statins improve blood cholesterol levels primarily by inhibiting a liver enzyme called HMG Co-A reductase, thus reducing the liver's ability to make cholesterol. Statins cause a significant reduction in LDL cholesterol levels, a moderate reduction in triglyceride levels, and a small increase in levels of HDL cholesterol.

Hope it helps,

Jon
Blank
Post a Comment
To
Top Heart Disease Answerers
976897_tn?1379171202
Blank
ed34
watford, United Kingdom
159619_tn?1318997813
Blank
erijon
Salt Lake City, UT
63984_tn?1385441539
Blank
Flycaster305
97303, OR
612551_tn?1247839157
Blank
Jerry_NJ
NJ
Avatar_f_tn
Blank
skydnsr
212161_tn?1391090750
Blank
heartfluttersflyawayplz
hoschton, GA
MedHelp Health Answers
Blank
BloodPressure Tracker
Monitor Your Blood Pressure
Start Tracking Now
Blank
HeartRhythm Tracker
Track your Heart Condition
Start Tracking Now
Recent Activity
1755089_tn?1376057155
Blank
drewlevas uploaded new photos
10 hrs ago
Avatar_m_tn
Blank
jave123 added the Heart Rhythm Tracker
22 hrs ago
Avatar_m_tn
Blank
keltan commented on Attention All Mouth B...
Aug 22
Heart Disease Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating: What Your Closet ...
Jul 09 by Roger Gould, M.D.Blank
Top Heart Disease Answerers
976897_tn?1379171202
Blank
ed34
watford, United Kingdom
159619_tn?1318997813
Blank
erijon
Salt Lake City, UT
63984_tn?1385441539
Blank
Flycaster305
97303, OR
612551_tn?1247839157
Blank
Jerry_NJ
NJ
Avatar_f_tn
Blank
skydnsr
212161_tn?1391090750
Blank
heartfluttersflyawayplz
hoschton, GA