Long-term use of Beta blockers

Dear Doctor, I

[Cleveland Clinic]

fran,

thanks for the post.

1. Will taking a BB daily lesen its effect in the long-run as the body gets used to it? If so what will the option be: to increase the dose, or switch to a different BB?

Generally not, while at the cellular level there are changes in the the number of receptors, clinically most do not develop major resistance to the drugs with respect to heart rate and blood pressure. If you happen to develop resistance, titrating the dose or finding another drug is fine.

2. On the other hand, may taking the BB daily help prevent bad exacerbation of symptoms, as the body absorbs the BB constantly every day?

I dont understand this question. There is nothing wrong with either intrmittant use or long term use of beta blockers. I would do whichever makes you feel best.

3. Taking Inderal as needed always worked wonders for me. Then one night last Feb, after working out at the gym, my heart just couldn

[Fran71]

Thanks so much again, doctor.
I know my second question was hard to phrase. I meant to ask if there may be a good benefit associated with the long-term use of a beta blocker. I was just guessing that maybe next time I have a drastic rise in adrenaline, my heart might react better since my body has been absorbing the BB for months now, being on the BB daily.
I'm so happy to hear that the Inderal may continue to work for me. I agree I'm very lucky to get such big relief from Inderal, for now.

Thanks again. This service is priceless.

Fran