Metoprolol

[Noni224]

I have taken Toprol xl 25 mg for about 5 years. My doctor switched me to metoprolol several months ago. When I filled my prescription this time, it was from a different mfg and I think I may be having problems with it as I just don't feel right. Could changing the mfg make a difference? ALSO, my doctor prescribed 50 mg to be cut in half for my prescribed 25 mg dose. Does cutting this tablet in half compromise the time release?

Thank you for your reply

[Cleveland Clinic]

Although it doesn't make much sense scientifically, some patients don't tolerate certain formulation as well as others.  Sometimes, it is not so much the actual drug but the makeup of the pill (other components such as binders, etc) that some patients may not tolerate well.  As far as splitting the pill, it is not a problem with metopolol.  But there are some pills that shouldn't be split.  Consider going back to the original torpol XL.

[LukeL]

you won't be on a time release with standard metoprolol that is why you need to take it twice a day. I don't know why you have to cut in in half, Wal-Mart has generic metoprolol in 25mg tablets for $4.00 per 30

The problem with cutting a pill in half is that while the whole tablet contains 50mg of medicine, you don't know if it is evenly dispersed thorught out the whole tablet (it should be though)

Many people report these types of things when switching from a brand name to a generic. Just look up coumadin vs warfarin.  

Did you doctor change your script for insurance reasons?