Posted By CCF Cardio MD-SGM on January 30, 1998 at 15:26:03:
In Reply to: Mitral regurge and leaflet thickening posted by d. Long on January 28, 1998 at 12:42:52:
: Ihave a 33 yr old friend with a longstanding history of CNS Lupus. She has recently had an acho for symptoms of dull chest pressure and the echo showed mild mitral regurgitation with some thickening of the leaflets. This is a change from an echo done a year ago which showed a slight mitral regurgitation, and no mention of thickening of the leaflets. Could this be, in any way, linked to her Lupus? Is it correct to assume there is some progression of the problem as there is now some amount of leaflet thickening noted? What would be the prudent course of action for follow-up? What symptoms or warning signs should send her for further evaluation or treatment? Thanks for any insight you can add...
Dear Ms. Long,
Lupus can indeed affect the heart, classically in the form of something known as verrucous endocarditis. This commonly appears as a bumpy malformation on the internal lining of the heart, occasionally associated with regurgitation of the mitral valve. Also, long term therapy with steroids can cause a variety of cardiac side-effects which are not directly related the topic at hand.
The findings you describe don
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