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Heart Disease  (Expert Forum)
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PAF & Sotalol
This forum is for questions and support regarding heart issues such as: Angina, Angioplasty, Arrhythmia, Bypass Surgery, Cardiomyopathy, Coronary Artery Disease, Defibrillator, Heart Attack, Heart Disease, High Blood Pressure, Mitral Valve Prolapse, Pacemaker, PAD, Stenosis, Stress Tests.

PAF & Sotalol

by Bil__0__0, Jun 10, 1998 12:00AM

  I have been diagnosed with Paroxsysmal(?) Atrial Fibrilation since 11/96. I am a 34 year old male with no other significant medical issues (except for GERD). I was diagnosed with Mitral Valve prolapse in 1982 but when the first episode of A-Fib happened in 11/96, they told me that I did not have a MVP but that I had a 'floppy mitral valve'.  Also, I do not have any problems with my Thyroid and the EKG indicates that there is no underlying structual defect in my heart. I was initially put on Digoxin & Lopressor. I felt really crappy on them & discontinued the Digixon and lowered the dose of Lopressor to 50mg a day after talking to my Dr. He told me that that dosage of Lopressor might not be effective at controlling the A-Fib. He was right. I had another episode in 9/97 & again in 1/98. After the last one I was put on Sotalol 80mg twice a day. Now I feel even worse than I did before. I'm constantly tired & feel drugged and have a marked decrease in my sex drive. My question is: are there any other drug therapies that do not have these types of side affects (i.e. flecanide or amiodarone) or is it just trial & error? Also, can you tell me about other alternatives such as implants or ablation for A-Fib? Are they available and are they appropriate for my situation?
  Any information would be greately appreciated. Thanks!
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Dear Bill:
Sotalol has properties similar to the Lopressor.  Sexual dysfunction is a well-recognized side effect.  However, I urge you not to discontinue any of your medicines abruptly without talking to your doctor.  Amiodarone can be a useful drug for atrial fibrillation.  It does have lots of potential side effects, but these are not usually too much of a problem with the low doses of amiodarone that are typically used for atrial fibrillation.  Flecainide can also have side effects; it is a drug to be avoided if there is any evidence or chance of having structural heart disease or coronary heart disease.  I think that an appropriate medication can be found for you, but it will be through trial and error.]
Only if medications fail would I recommend pursuing experimental therapies.  This includes catheter ablation for atrial fibrillation, a procedure a few medical centers are doing.  Another experimental option is an implantable atrial defibrillator - it gives your heart a tiny shock when it goes into atrial fibrillation.  Again, I would not pursue these options yet.
I hope this information has been useful to you.
Information provided here is of a general nature.  Specific diagnoses and treatments can only be made by your doctor.  If you would like to be seen at the Cleveland Clinic, please call 1-800-CCF-CARE for an appointment with a cardiac electrophysiologist at Desk F15.





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