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I've had severe PVC's and was told these were "normal" and there was nothing that could be done. Through some online research, i ran across an article that linked Magnesium deficiency to PVC's or heart arhythmias. I've been taking the RDA of Magnesium through an over-the-counter supplement, and my PVC's have significantly decreased. Not sure if it will work for everyone, but it seems a safe and easy solution and may be worth a shot.