Hello,
One of my mentors told me once that the people who need SSRI (the class of medications as Zoloft) are the same people that are too anxious to take them. I think it is worth trying and I often to talk to my patients about considering them. Package inserts always list alarming or frightening side effects -- they have to. The reality is that SSRIs are very well tolerated and can be very effective. If they do increase your PVCs, yu can stop the medication and try a different one. They have many different receptor affinities and there may be some that help and others that don't. It might take a few tries to find one that does, but it is worth a try.
The only way to know what it will do for your palps or heart rate is try them. There is no way to know unless you try.
I hope this helps. Good luck and thanks for posting.
For ten years she went to doctors and psychiatrists. They did nothing for her except fill her full of medications that messed up her body.
My suggestion is that you look for a doctor who doesn't prescribe medications as the main way to treat anxiety but looks to deal with the underlying cause of the anxiety. There are doctors out there, but they look at medicine outside the typical medication regime. Also find a counselor that can help sort through the pscyhological reasons for anxiety. Deal with the cause, not the symptoms.
Thanks
"SSRIs may reduce platelet aggregation. Many patients with depressive illness have dysregulation of the sympathoadrenal system as evidenced by an elevated plasma level of norepinephrine. Data suggest that increased catecholamine activity increases platelet activation and aggregation contributing to thrombus formation, and studies of both healthy depressed patients and depressed patients with IHD have documented increased platelet activation compared with nondepressed controls (18, 19). The SSRIs interfere with serotonin accumulation in platelets and SSRI treatment normalizes elevated indices of platelet activation in patients with depression and IHD."
Interesting to note that Wellbutrin is said to suppress 82% of PVC's in patients.
"Bupropion (Wellbutrin) caused a statistically significant 5 mm Hg increase (p < .01) in supine systolic and a 3 mm Hg (p < .005) increase in supine diastolic blood pressure and a statistically significant increase in orthostatic drop (3 mm Hg; p < .02). There was no significant effect observed on heart rate, ejection fraction, or cardiac conduction. However, bupropion did cause 82% suppression of ventricular premature depolarization (p < .005). Five patients had to be withdrawn from the study because of adverse effects, and 4 of the 5 cases the events were cardiovascular."
http://www.psychosomaticmedicine.org/cgi/content/full/67/Supplement_1/S54
A note though... just because Wellbutrin can suppress 82% of PVC's does not mean you're not going to face an increased risk of a heart attack. In fact, suppressing PVC's can cause more deaths than leaving PVCs alone in selected patients. It noted that 4 patients dropped out because of cardiovascular side effects (it didn't say what kind tho).
Try a natural approach first that doesn't bring all the negative side effects with it.
See a good counselor to deal with any psychological issues.
My wife took Wellburtrin for years. It didn't do any good. And it disturbed her sleeping. She finally followed the regime of the mood cure book and it worked. No side effects either.
I had a time where I was exhausted and the doctor thought I was depressed. He prescribed Zoloft and it sent me into panic attacks. I quicky went off of it.
I was then prescribed PAXIL. That didn't work. Made me agitated. I finally gave it up and just got more rest and exercise.
I have severe panic disorder and depression. I also have unifocal ventricular premature beats and rare atrial premature beats.
I was hospitalised for a few weeks in a pysch ward.
The pyschs put me on Zoloft and I was terrified thinking it was going to make my missed beats worse. I was so scared I had to be forceably sedated. I ended up taking Zoloft and was awake for three days and nights.
I have had no other symptoms and my missed beats have not got worse. I have been on Zoloft now for 3 years.
Forget all the warnings and the doomsayers. If you have been prescribed it, take it. It helped and still helps me.
As the doctor says, one SSRI will work nicely for one person, and not for another, so you just have to try them on, so to speak. And speaking for myself, I get panic attacks every few years whether I need them or not. They are invariably accompanied by lots of pvcs (10K a day confirmed by Holter), and for me, zoloft taken for a few months just takes care of the whole syndrome: First the panic goes away (and fast, because I respond very quickly to zoloft), with the result that I also become less aware of the odd beats. In a couple of weeks, either the pvcs become less frequent or I just care less, and finally, after a month or two, they simply go away. I have noticed no speeding up of my heart rate, btw.
I usually stay on the drug for a couple of months after that, because my shrink says it's best to let the hyperactive alarm system quiet down, and then I taper off.
Interestingly, I don't do as well on Paxil or Lexapro (the "son" of Celexa, which did once work quite well for me).
Anyhow, the point is that it's well worth a try, even for the medicine-phobics, because you can always quit the SSRI (tapering off--not suddenly), and there really are not any long-term evil effects.
thank you
I just started having constant PVCs last week. I've had random ones occasionally for years (without knowing what they were), but last week I started having 10-15 per minute...that's roughly 15,000 - 20,000 per day. I went to the ER and they didn't seem very concerned, other than my BP which peaked at 179/98 (probably from worrying about the PVCs). They prescribed Metoprolol and I have taken it every day. My BP is now in the normal range, but the PVCs continue unaffected by the meds.
For the past several days, I have had a very dull headache and some slight dizziness in addition to the constant PVCs. I'm just wondering if anyone else has these additional symptoms. Are they the result of a lack of blood flow to the brain from the PVCs, or are they a side effect of the Metoprolol? Also, I've read that these PVCs are benign, but does that still hold true when I have thousands every day? It seems like they could be causing other problems. Any thoughts?
Thanks.
Ashley
As a student of psychology in college, I worked in the psych lab. When we did experiments, we had to list *everything* that happened during them, whether it was a consequence of the actual experiment or not. Similarly, during drug trials such as those for SSRI medications, ALL of the symptoms that subjects experience must be listed because that's just the way research is done to ensure the most accurate results. Now bear in mind that most people in these trials already had symptoms of restlessness, anxiety, palpitations, etc., because that is exactly what Zoloft and other SSRIs are prescribed for.
I hope that helps ease your mind a little. Hang in there. I hope you can find something that works for you :)
I thought Vodka was the initial cause, but in the past few months they show up without any alcohol consumption, and they almost always last for 5-6 days straight and disapear only to come back again for the same amount of time. I went to the cardiologist, an had a stress test and I am taking Toplrol XL, he said not to worry about them, but they are annoying especially when trying to study or sleep. I guess there is no cure for these things? I never heard of them before a year ago, and wish I never had.
My story is quite different. I was prescribed Celexa for anxiety some years ago which caused me to have a severe anxiety reaction. If you are already in a highly anxious state, SSRI's can exacerbate your symptoms temporarily (until the medication kicks in). I stayed on the medication at the advice of my doctor and was told that, in time, it would reduce my anxiety. At the time I was having very mild palpitations. Eventually, the medication did work and I had a significant reduction in anxiety for a couple of years. About a year ago, I began having severe bouts of PVC's while trying to go off the Celexa. Once I was completely off of it, my palpitations became so severe, I went back on the medication at a low dose and my symptoms improved. They have now worsened again and I am considering going up on my medication. However, I've been seeing a naturopath who, through blood tests, has found that I am anemic, vit B12 and D deficient, have low thyroid and am perimenopausal! She suggests that my gluten sensitivity could be causing malabsorbtion of many vital nutrients needed to keep the heart and other organs functioning properly. Has anyone explored the connection between gluten and heart rhythm problems? If so, I would love to hear your comments.
Maybe you could try some different Beta Blockers to see if they make any difference. I think things have moved on since propranalol was introduced nearly thirty years ago. Good Luck. John.
I'm 40 yrs old. On Tuesday (today is Friday), I had a bad "flutter" and since then, my heart beat has been off. I can feel it in my pulse. I went to the emergency department, they told me it was PAC's. (confirmed by the heart monitor). I had blood tests, ekg and stuff and all was normal. It happens up to 20 times a minute sometimes but it has been constant since Tuesday. I'm scared to death. I went to my GP who has referred me to a cardiologist. I've read on the forums about others and it has comforted me somewhat. I have to keep moving though because they seem to lessen with exercise. I'm exhausted becasue I haven't stopped for 4 days. When I rest, it seems worse. Has anyone else been like this? It feels like I'm going to have a heart attack at any minute. I can't understand how this is benign because you can actually feel your heart doing something that's not normal. If you have stories like this, please let me know. It's comforting to see others with the same thing, even though I wouldn't wish this on my worst enemy. I've read about drugs such as Atenenal that work, as well as magnesium supplements. Does anyone have any suggestions about what I could try? How long have yours lasted. Thank you so much for any help you can provide.
THanks,
Craig
I'm 40 yrs old. On Tuesday (today is Friday), I had a bad "flutter" and since then, my heart beat has been off. I can feel it in my pulse. I went to the emergency department, they told me it was PAC's. (confirmed by the heart monitor). I had blood tests, ekg and stuff and all was normal. It happens up to 20 times a minute sometimes but it has been constant since Tuesday. I'm scared to death. I went to my GP who has referred me to a cardiologist. I've read on the forums about others and it has comforted me somewhat. I have to keep moving though because they seem to lessen with exercise. I'm exhausted becasue I haven't stopped for 4 days. When I rest, it seems worse. Has anyone else been like this? It feels like I'm going to have a heart attack at any minute. I can't understand how this is benign because you can actually feel your heart doing something that's not normal. If you have stories like this, please let me know. It's comforting to see others with the same thing, even though I wouldn't wish this on my worst enemy. I've read about drugs such as Atenenal that work, as well as magnesium supplements. Does anyone have any suggestions about what I could try? How long have yours lasted. Thank you so much for any help you can provide.
THanks,
Craig