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Heart Disease  (Expert Forum)
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PVCs again
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PVCs again

by laramark, May 09, 2007 12:00AM
Are uniform PVC common in cardiomyopathies? My brother has dilated cardiomyopathy with EF 40% and frequent PVCs.
His EP study read that the PVC originated from automatic focus in the base of right ventricle (ablated succesfully).  Is this common in cardiomyoapthy? I read that there are several mechanisms of PVCs?

He has been tolerating lisinopril 20 mg well for several week. Now he feels dizzy and lightheaded. His blood pressure is 90/60 and 100/70. Does that mean his EF went down? Is this common in cardiomyopathy that one suddenly cannot tolerate medication?

thanks

by Forum-M.D.-bkj, May 09, 2007 12:00AM
Lara,

Thanks for the post.

PVCs are common even without cardiomyopathy. Depending on the mechanism underlying cardiomyopathy, PVCs may be more frequent. There of course is a lot of variability in the disease since there are multiple causes of cardiomyopathies.

Dizziness can be caused by a large number of things both cardiac and non cardiac in etiology. I would not really think his EF dropped. However, he should be evaluated for his symptoms.

Medication intolerance occurs as medications are altered in any disease. It takes several weeks for the full effects of medications to be realized so I would think that this is probably due to his recent changes.

good luck
Member Comments (3)

by Momto3, May 09, 2007 12:00AM
To: laramark
Not sure if this will help, but when I've had to cut back on lisinopril b/c of lightheadness and low BP.  I felt so lethargic until the dose was adjusted.

Has your brother's CM been correlated to pvcs?  I developed CM as a result of frequent (thousands/day) pvcs.  It is not common, but it does happen.  Once the pvcs were treated (ablated), the CM resolved.

by laramark, May 09, 2007 12:00AM
To: momto3

He seems to be tolerating lisinopril for several weeks and then suddently lightheadnedness and low blood pressure.

Yes, we read few of your responses and we are encorouged by it.
The cardiologists mentioned the PVC causing cardiomyopathy but they are not sure. As I am reading, cardiomyopathy usually causes PVCs and it is related to scar tissue. His PVCs were (per report) not originating from the scar. So we are not sure if that means anything, eg good or bad signs and how many different types of PVCs there are.
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