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I am trying to find the cause of the PVC's that I have had since November, which have gotten worse. The past 10 days I have had them constantly at 1200 per hour and feel terrible. The dr. wants to do an ablation. On searching the internet, I came across alot of message boards that say that alot of people have had many side effects, including arrythmias, when they were switched from name brand ToprolToprol-xl XL to the generic version. I was on ToprolToprol-xl XL for over 10 years with no problems. I was switched by my drug company last October and the PVC's started in November. In Feb, I was switched again to generic LopressorLopressor Lopressor hct, which from what I heard, is the same things only not extended-release. Has anyone experienced problems with the generic form of either drug or have heard of others having problems?