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Heart Disease (Expert Forum)
Re: Antibiotics with MVP
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Re: Antibiotics with MVP
by Lori-T, Jan 01, 1995 12:00AM
Posted By Lori T on November 12, 1998 at 11:04:51:
In Reply to: Re: Antibiotics with MVP posted by CCF CARDIO MD-APS on November 10, 1998 at 17:48:35:
Dear Doctor,
I have a question regarding MVP. I was diagnosed with MVP with slight
thickening and trace regurgitation and possible slight aortic valve
thickening. I was told that I need to take antibiotics before dental
work and any kind of surgery. I would like to know what else I would need
to take antibiotics for. Is these a web site to go to that lists the
recommendations. For example, if you go to a doctor and get a (I am not
sure how to spell this) nasocopy (where they insert a thin tube (with
laser) down your nose, or when you go to a gastrointerologist and in his
office he needs to use a rectal scope, or if you get your legs or armpits
waxed (I know this sounds stupid - but I just am not sure and do not
want to take chances).
Recently I had to get minor skin surgery and was medicated. I am knew
to this and called the cariologists office to get a perscription. I told
the nurse that I was allergic to Ceflex (I am not sure if it spelled this
way or Keflex (a cefolasporin)) so that I don't think I could take
Amoxicilan. I told her for sinus infections (which I get alot) I ususally
take Biaxin. So she called in a perscription for Biaxin of 4 (four) 500 mg
stregth to be taken one hour before the appointment. I took the four and
got deadly ill. I felt nausea, dizzy, severe stomach pain and chest pain and
felt like I would pass out. I spoke with my cardiologists associate and
he told me that the dose was incorrect. That I should have only been given
one Biaxin (500 mg) not four. Could you please let me know first is this
correct one Biaxin will do the job, and the second thing is that I felt
like I was poisoned. Could this dosage have done anything to my internal
organs.
Sorry for such a long message.
Thank you so much for any insight.
Lori T
____
: Dear Lori,
Prophylaxis for bacterial endocarditis (i.e. taking antibiotics prior to a procedure to avoid infection of the heart valves)
is recommended for any dental, oral, respiratory tract, gastrointestinal, and or genitourinary procedure.
There is no evidence that waxing hair of the armpits or legs results in transient bacteremia (bacteria in blood) and therefore it is not necessary to take the precaution.
Just because you have an allergy to cephalosporins, this does not mean you are allergic to penicillin and amoxicillin. Clarithromycin is famous for the gastrointestinal side effects that you experienced, and not surprising given the large dose that you took.
Although you may not have any such effects if you take the proper dosage (500mg, one pill 1 hour prior to the procedure), you may want to try the well tolerated azithromycin- one 500mg pill 1 hour prior to thr procedure. Just so that you know, the recommendations are for higher doses in the case of genitourinary and non-esophageal GI procedures.
It is highly unlikely that the large dose of clarithromycin did any damage to your internal organs as you say,
but if you are still having symptoms of nausea and diarrhea, etc. then you would need medical evaluationof the same and still it is highly unlikely to be related to the dose of antibiotics that you took.
Good Luck and write back if you have any further questions. If you want to know, the article with recommendations for antibiotic prophylaxis was published in the Journal of the American Medical Association (JAMA) in 1997, this is available at any medical library to anyone.)
Information provided in the heart forum is intended for general medical informational purposes only,
actual diagnosis and treatment can only be made by your physician(s).
Dear Doctor,
Thank you very much for your answers. I have just a couple of more questions.
I have been told by several people (not professionals) that a sinus infection
(bacterial) if left untreated could affect the mitral valve, if you have MVP.
Is this true of a sinus infection, or any other infection in the body (i.e.,
vaginal infection).
The second question is regarding vegetations. What exactly are they? And what
are there significance with someone with a connective tissue disorder (i.e.
Lupus). (Can vegetations be prevented in a person with Lupus?). Can
vegetations be detected with just an echocardiogram?
Thank you so much again (and I am sorry - I believe I had more than 2 questions)
Thanks Lori
In Reply to: Re: Antibiotics with MVP posted by CCF CARDIO MD-APS on November 10, 1998 at 17:48:35:
Dear Doctor,
I have a question regarding MVP. I was diagnosed with MVP with slight
thickening and trace regurgitation and possible slight aortic valve
thickening. I was told that I need to take antibiotics before dental
work and any kind of surgery. I would like to know what else I would need
to take antibiotics for. Is these a web site to go to that lists the
recommendations. For example, if you go to a doctor and get a (I am not
sure how to spell this) nasocopy (where they insert a thin tube (with
laser) down your nose, or when you go to a gastrointerologist and in his
office he needs to use a rectal scope, or if you get your legs or armpits
waxed (I know this sounds stupid - but I just am not sure and do not
want to take chances).
Recently I had to get minor skin surgery and was medicated. I am knew
to this and called the cariologists office to get a perscription. I told
the nurse that I was allergic to Ceflex (I am not sure if it spelled this
way or Keflex (a cefolasporin)) so that I don't think I could take
Amoxicilan. I told her for sinus infections (which I get alot) I ususally
take Biaxin. So she called in a perscription for Biaxin of 4 (four) 500 mg
stregth to be taken one hour before the appointment. I took the four and
got deadly ill. I felt nausea, dizzy, severe stomach pain and chest pain and
felt like I would pass out. I spoke with my cardiologists associate and
he told me that the dose was incorrect. That I should have only been given
one Biaxin (500 mg) not four. Could you please let me know first is this
correct one Biaxin will do the job, and the second thing is that I felt
like I was poisoned. Could this dosage have done anything to my internal
organs.
Sorry for such a long message.
Thank you so much for any insight.
Lori T
____
: Dear Lori,
Prophylaxis for bacterial endocarditis (i.e. taking antibiotics prior to a procedure to avoid infection of the heart valves)
is recommended for any dental, oral, respiratory tract, gastrointestinal, and or genitourinary procedure.
There is no evidence that waxing hair of the armpits or legs results in transient bacteremia (bacteria in blood) and therefore it is not necessary to take the precaution.
Just because you have an allergy to cephalosporins, this does not mean you are allergic to penicillin and amoxicillin. Clarithromycin is famous for the gastrointestinal side effects that you experienced, and not surprising given the large dose that you took.
Although you may not have any such effects if you take the proper dosage (500mg, one pill 1 hour prior to the procedure), you may want to try the well tolerated azithromycin- one 500mg pill 1 hour prior to thr procedure. Just so that you know, the recommendations are for higher doses in the case of genitourinary and non-esophageal GI procedures.
It is highly unlikely that the large dose of clarithromycin did any damage to your internal organs as you say,
but if you are still having symptoms of nausea and diarrhea, etc. then you would need medical evaluationof the same and still it is highly unlikely to be related to the dose of antibiotics that you took.
Good Luck and write back if you have any further questions. If you want to know, the article with recommendations for antibiotic prophylaxis was published in the Journal of the American Medical Association (JAMA) in 1997, this is available at any medical library to anyone.)
Information provided in the heart forum is intended for general medical informational purposes only,
actual diagnosis and treatment can only be made by your physician(s).
Dear Doctor,
Thank you very much for your answers. I have just a couple of more questions.
I have been told by several people (not professionals) that a sinus infection
(bacterial) if left untreated could affect the mitral valve, if you have MVP.
Is this true of a sinus infection, or any other infection in the body (i.e.,
vaginal infection).
The second question is regarding vegetations. What exactly are they? And what
are there significance with someone with a connective tissue disorder (i.e.
Lupus). (Can vegetations be prevented in a person with Lupus?). Can
vegetations be detected with just an echocardiogram?
Thank you so much again (and I am sorry - I believe I had more than 2 questions)
Thanks Lori
