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Heart Disease (Expert Forum)
Re: Cholesterol #'s
This forum is for questions and support regarding heart issues such as: Angina, Angioplasty, Arrhythmia, Bypass Surgery, Cardiomyopathy, Coronary Artery Disease, Defibrillator, Heart Attack, Heart Disease, High Blood Pressure, Mitral Valve Prolapse, Pacemaker, PAD, Stenosis, Stress Tests.
Re: Cholesterol #'s
by Cleveland Clinic, MD, Jan 01, 1995 12:00AM
, Jan 01, 1995 12:00AM
Posted By CCF CARDIO MD - CRC on February 23, 1999 at 15:40:54:
In Reply to: Cholesterol #'s posted by Heather on February 22, 1999 at 13:48:18:
I Had blood work done and the nurse called back and said I had high cholesterol. She wanted to make me an appointment to see a lipid doctor to talk over my options. My Numbers are 154 LDL and 72.3 HDL. I am only 25 years old, 5`5 110 pounds with tachycardia and high Bp upon standing. I don't work out any more due to the tachycardia(I know i should) My mother died of an arrythemia due to a 90% block in one cornary artery at 46(but she was overweight) and her brother had a quadrupal bypass at 54. How concerned should i be. Should someone my age be put on cholesterol lowering drugs. I don't really watch what I eat and don't put on weight. i thought weight and cholesterol went together. Are there any medicines that may raise you cholesterol. I take nadolol, clonidine and flovent. I am not currently taking the clonidine but was taking it when the blood work was done. I am hoping to have children some day I am already concerned about the Bp upon standing do I also have to worry about the cholesterol during pregnancy. Thank you
Heather
Dear Heather,
Thank you for your question. First of all let me say that information presented here is not intended to replace the advice of your personal physician. He/she is the one who knows your particular case the best and will make recommendations that are specific to you. So I would recommend following your doctor's advice for treatment questions.
Cholesterol has been identified as a major risk factor in the development of heart disease. Early studies established high cholesterol as a risk factor for developing heart disease. Lowering cholesterol for secondary prevention, that is preventing second heart attacks in persons who already had had one, was next demonstrated in the eighties and primary prevention of heart attack and stroke (In persons who had never had a prior event) demonstrated in the nineties. The most recently published studies have demonstrated that lipid lowering therapy decreases cardiac events even in those persons with normal cholesterol.
Total cholesterol is broken down into different categories. High density cholesterol (HDL) is the "good cholesterol" that acts as a cleaning cholesterol. Low density cholesterol (LDL) is the "bad cholesterol" that clogs up arteries throughout the body. LDL is not usually measure directly but is calculated from the following equation: LDL=Total-HDL-triglycerides/5. If the triglycerides are too high the LDL calculation is not valid. Triglyceride is another type of cholesterol whose significance is not well established. Very high levels (>1000) can lead to pancreatitis and other health problems. Cholesterol should be measured after an 8 hour fast.
Guidelines have been established as to the treatment of high cholesterol. It has been recommended that everyone over that age of 25 has their total cholesterol and HDL measured. If these are abnormal a full cholesterol panel should be done. Guideline for the treatment of cholesterol depend upon the risk factors that the person has. Risk factors are a family history of heart disease, high blood pressure, male >45 yrs or female >55 yrs, diabetes (counts as two risk factors), smoking and obesity. Someone at low risk should have a goal LDL cholesterol less than 130 and should be on a special diet if LDL is greater than 160 and on medication if it is greater than 190. Someone with one or two risk factors should start medical treatment at 160. Someone with more than two risk factors or with established heart disease should have a goal LDL of less than 100 with medical treatment started at 130.
Medical treatment of cholesterol includes resins which bind cholesterol, niacin, gemfibrazole (useful for elevated triglycerides) and statins. All of the drugs except the resins may have a negative effect on the liver and liver function tests should be monitored. If there is an increase in the liver enzymes it is usually reversible if the drug is stopped. A rare but potentially serious side effect is myositis (muscle inflammation) and if muscle pain should occur the drug should be stopped and the prescribing doctor notified.
Further information can be found at the site below:
http://www.amhrt.org/Heart_and_Stroke_A_Z_Guide/chol.html
Information provided here is for general educational purposes only. Only your doctor can provide specific diagnoses and treatments. If you would like to be seen at the Cleveland Clinic, please Call 1 - 800 - CCF - CARE for an appointment at Desk F15 with a cardiologist.
In Reply to: Cholesterol #'s posted by Heather on February 22, 1999 at 13:48:18:
I Had blood work done and the nurse called back and said I had high cholesterol. She wanted to make me an appointment to see a lipid doctor to talk over my options. My Numbers are 154 LDL and 72.3 HDL. I am only 25 years old, 5`5 110 pounds with tachycardia and high Bp upon standing. I don't work out any more due to the tachycardia(I know i should) My mother died of an arrythemia due to a 90% block in one cornary artery at 46(but she was overweight) and her brother had a quadrupal bypass at 54. How concerned should i be. Should someone my age be put on cholesterol lowering drugs. I don't really watch what I eat and don't put on weight. i thought weight and cholesterol went together. Are there any medicines that may raise you cholesterol. I take nadolol, clonidine and flovent. I am not currently taking the clonidine but was taking it when the blood work was done. I am hoping to have children some day I am already concerned about the Bp upon standing do I also have to worry about the cholesterol during pregnancy. Thank you
Heather
Dear Heather,
Thank you for your question. First of all let me say that information presented here is not intended to replace the advice of your personal physician. He/she is the one who knows your particular case the best and will make recommendations that are specific to you. So I would recommend following your doctor's advice for treatment questions.
Cholesterol has been identified as a major risk factor in the development of heart disease. Early studies established high cholesterol as a risk factor for developing heart disease. Lowering cholesterol for secondary prevention, that is preventing second heart attacks in persons who already had had one, was next demonstrated in the eighties and primary prevention of heart attack and stroke (In persons who had never had a prior event) demonstrated in the nineties. The most recently published studies have demonstrated that lipid lowering therapy decreases cardiac events even in those persons with normal cholesterol.
Total cholesterol is broken down into different categories. High density cholesterol (HDL) is the "good cholesterol" that acts as a cleaning cholesterol. Low density cholesterol (LDL) is the "bad cholesterol" that clogs up arteries throughout the body. LDL is not usually measure directly but is calculated from the following equation: LDL=Total-HDL-triglycerides/5. If the triglycerides are too high the LDL calculation is not valid. Triglyceride is another type of cholesterol whose significance is not well established. Very high levels (>1000) can lead to pancreatitis and other health problems. Cholesterol should be measured after an 8 hour fast.
Guidelines have been established as to the treatment of high cholesterol. It has been recommended that everyone over that age of 25 has their total cholesterol and HDL measured. If these are abnormal a full cholesterol panel should be done. Guideline for the treatment of cholesterol depend upon the risk factors that the person has. Risk factors are a family history of heart disease, high blood pressure, male >45 yrs or female >55 yrs, diabetes (counts as two risk factors), smoking and obesity. Someone at low risk should have a goal LDL cholesterol less than 130 and should be on a special diet if LDL is greater than 160 and on medication if it is greater than 190. Someone with one or two risk factors should start medical treatment at 160. Someone with more than two risk factors or with established heart disease should have a goal LDL of less than 100 with medical treatment started at 130.
Medical treatment of cholesterol includes resins which bind cholesterol, niacin, gemfibrazole (useful for elevated triglycerides) and statins. All of the drugs except the resins may have a negative effect on the liver and liver function tests should be monitored. If there is an increase in the liver enzymes it is usually reversible if the drug is stopped. A rare but potentially serious side effect is myositis (muscle inflammation) and if muscle pain should occur the drug should be stopped and the prescribing doctor notified.
Further information can be found at the site below:
http://www.amhrt.org/Heart_and_Stroke_A_Z_Guide/chol.html
Information provided here is for general educational purposes only. Only your doctor can provide specific diagnoses and treatments. If you would like to be seen at the Cleveland Clinic, please Call 1 - 800 - CCF - CARE for an appointment at Desk F15 with a cardiologist.
