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Recently diagnosed with accelerated atherosclerosis

by zobie, Jul 26, 2008 12:54AM
I have just been diagnosed with accelerated atherosclerosis. Has anyone been diagnosed with this? Can you tell me what it is?

Thank You
Zoe
Member Comments (1)

by kenkeith, Jul 28, 2008 09:38AM
To: zobie
The condition is vascular injury the underlying cause can be due to a metabolic syndrome, insulin resistance, prediabetes, and overt type 2 diabetes mellitus are associated with an accelerated atherosclerosis (atheroscleropathy).

The common (spontaneous atherosclerosis) pathophysiologic mechanisms, namely, endothelial injury with early platelet involvement and subsequent progressive smooth muscle cell proliferation and thrombosis leading to vascular occlusion. Understanding the mechanisms of this process has made it possible to include strategies to limit vascular injury and reduce subsequent thrombotic and proliferating cellular responses.

In contrast to spontaneous atherosclerosis, a more significant denuding endothelial injury appears to be the critical initiating event, followed by intense platelet involvement and thrombus formation, leading to an initial predominant process of smooth muscle cell proliferation in accelerated atherosclerosis. Risk factors like cigarette smoking and hypertension play an important role in this process.
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