Hello, I am an otherwise healthy 52 year female. I began having symptomatic PVC's in about 2008. Echo normal, scan showed mild attenuation on distal anterior wall, stress test negative, EKG normal aside from frequent PVC's. These episodes have come and gone over the years, lasting a day to weeks at a time. In January of this year they became quite severe and non-stop with holter monitor showing about 7000 in 18 hours. I feel every one of them which effects my ability to fall asleep, causes SOB, chest tightness, fatigue and near syncope. There has been no correlation to activity, caffeine, alcohol, stress, etc. Echo was then showing mild mitral and tricuspid regurgitation and mildly elevated RVSP (40's). After failing at several medicinal trials my EP attempted an ablation...but the ectopic activity stopped a couple days before procedure and he was unable to induce a single one during a grueling non-sedated 5 hour period. They have continued to be sporadic but seem to be increasing in severity again over the last couple of weeks. EKG now shows a short PR interval in the 90's and has always been >120. From what I have researched it sounds like this can put me at greater risk for life threatening arrhythmias. I read one discussion regarding placing a pacemaker and ablating the AV node in certain cases. QRS is normal and without delta wave so doesn’t fit WPW profile, but does appear to fit LGL. Those are only 2 pre-excitation syndromes I could find. I will be seeing my EP next week. Does anyone have any further insight or am I being overly concerned? Thank you!