Heart rate, blood pressure, and the left ventricle ejection percentage are interelated to maintain a balance of blood flow between the right and left side of the heart. These mechanisms would be interrrelated. The low blood supply (volume in circulation) the kidneys will increase the volume (an example would blood loss, or a low cardiac output).
The left venticle will dilate to increase blood flow with each stroke and the heart rate will increase the cardiac output (amount of blood pumped per minute).
If the system is dysfunctional, medication, etc. can change the dynamics. For instance heart failure increases blood volume and the kidneys react as if the individual is losing blood...the increase of volume further distresses the heart and kidneys continue to believe the system is losing blood. Also, the heart rate and dilation of the heart will continue to rise with a low cardiac output. So medication is needed to intervene to keep the volume of blood normal, medication to keep the heart rate within an acceptable range, and medication to help decrease heart size for a normal ejection fraction.
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