I was in hospital last week for dehydration & electrolytes being messed up. Also had kidney infection. The hospitalist increased my Digoxin from .12mg to 125mcg. I have been on present dose for 10 yrs. I'm afraid to increase by this much. I see my internist on 4/27 and will ask him.
crow260
It is difficult to provide an answer to your questions as there some many variables involved with general health, etc.
I was on digoxin for about 6 months after a chf episode (recovered rather quickly) and for 5 1/2 years I have not taken the medication. I was on a diuretic at the time as well. Heart failure individuals who take digoxin are commonly given diuretics, which remove excess fluid from the body. Many diuretics can cause potassium loss. Low levels of potassium in the body increase the risk of digitalis toxicity. Digitalis toxicity may also result in persons who take the drug and who have low levels of magnesium in the body.
Risks include taking digitalis medications such as digoxin or digitoxin along with medications that interact with digitalis such as quinidine, verapamil, amiodarone, and others.
Reduced kidney function will cause digitalis to build up in the body rather than be removed normally through urine. Therefore, any disorders that disrupt kidney functioning (including dehydration) make digitalis toxicity more likely.
Generally, most drugs should be gradually increased and monitored. And going off a drug should be gradual as well so the body's system can adjust to the change.
With chf the heart's contractions are weaker than normal, and digoxin helps provide a stronger beating heart. If one has increased functionality of the heart, the drug may be dropped, also, there can be a tolerance that develops with digoxin that may require discontinuation for a period of time.