Heart Disease Community
nitro patch + withdrawal or something else
About This Community:

Join others with Heart Disease and get guidance and support. Ask a question, join a conversation, share experiences.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

nitro patch + withdrawal or something else

I have been on the nitro-dur patch since Friday and forgot to take it yesterday.  I woke up this morning and now my bp is 185/110.  Can withdrawal of the nitro patch cause high blood pressure, even though I've only been taking it for three days now?
Related Discussions
10 Comments Post a Comment
Blank
976897 tn?1379171202
absolutely, the nitro patch is there to dilate your arteries, enabling more blood to flow. Once the Nitrates have reduced, your arteries will constrict again, raising blood pressure. Nitrates are very quick reacting which is why they are administered to heart attack victims.
Blank
Avatar n tn
Thanks for your input...my bp is slowly dropping now, so I guess the nitro is finally kicking in.
Blank
367994 tn?1304957193
ed is correct nitro dilates vessels.

I take a nitrate (isosorbide) for more than 6 years 3 times before going to gym for workout.  My blood pressure does not drop between intervals...in fact I was told to have intervals of nitrate free period.  It is true, nitro dilates the coronary vessels and prevents angina (chest pain).  The patch should only be worn for up to 12 to 14 hours a day, or as directed by your doctor, but continued use with no interruptions can cause a tolerance for drug....It is important to have a "nitrate-free" period of time each day for Nitroglycerin Patch to continue to work well and to decrease the risk of physical dependence.

Maybe the anxiety of missing a dose caused anxiety causing an increase in BP. "Some people who use Nitroglycerin Patch for a long time without a break may develop a physical need to continue taking it. This is known as physical DEPENDENCE. If you use Nitroglycerin Patch without a break and then suddenly stop using it, you may get WITHDRAWAL symptoms. No high bp but may include chest pain, heart attack, or possibly sudden death. Be sure to have a "nitrate-free" period of time each day; this may help prevent dependence and withdrawal problems".

Read more: http://www.drugs.com/cdi/nitroglycerin-patch.html#ixzz0xRS9k6y4

If you continue to have episodes of high blood pressure, you may want to contact your doctor.

Blank
Avatar n tn
Thanks, Kenkeith, for your input too.  I understand what you are saying about the possibility of anxiety from missing a dose causing my bp to increase, but I actually wasn't even thinking that there could be any withdrawal symptoms from not wearing the patch, so I doubt that it is anxiety.  I simply took my bp this morning as I usually do, and lo' and  behold it was high.
I do have the break in treatment - I am to put the patch on at 8am and take it offf at 10pm, which I have done until yesterday.
Blank
367994 tn?1304957193
It appears you are doing everything right and the interval should be effective to prevent tolerance. Steady-state plasma concentrations of nitroglycerin are reached by about two hours after application of a patch and are maintained for the duration of wearing the system (observations have been limited to 24 hours). Upon removal of the patch, the plasma concentration declines with a half-life of about an hour.  If there were to be side effects, it seems it would be within hours.   Nitrates are not as effective (less strength) and have a longer half life so the same time constraints my not apply?!

Thanks for sharing your experience.
Blank
Post a Comment
To
Top Heart Disease Answerers
159619 tn?1318997813
Blank
erijon
Salt Lake City, UT
11548417 tn?1440481484
Blank
Ger57
Netherlands
Avatar m tn
Blank
caregiver222
Avatar f tn
Blank
achillea
CA
Avatar m tn
Blank
tacolino
Ireland
Blank
BloodPressure Tracker
Monitor Your Blood Pressure
Start Tracking Now
Blank
HeartRhythm Tracker
Track your Heart Condition
Start Tracking Now
Heart Disease Community Resources
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Heart Disease Answerers
159619 tn?1318997813
Blank
erijon
Salt Lake City, UT
11548417 tn?1440481484
Blank
Ger57
Netherlands
Avatar m tn
Blank
caregiver222
Avatar f tn
Blank
achillea
CA
Avatar m tn
Blank
tacolino
Ireland