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Heart Disease (Expert Forum)
tambocor and diazepam
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tambocor and diazepam
by bob__0__0, Jun 15, 1999 12:00AM
Posted by bob on June 15, 1999 at 11:50:29
hello doctors, I am on Tambocor (100mg BID) for chronic PAC's and PSVT (otherwise 25 yo healthy male). The medication works 16 hours out of the day completely but my EP doc wants to increase the med by another 100mg/d (for a total of 300mg/d) so it works 24 hours out of the day. Each time my Tambocor has been increased I get a stress test done because my doc said the higher dose may cause widening of the qrs interval which can lead to v tach. I'm claustrophobic and he prescribed my diazepam (5-10mg) to take before the test to relax me. My questions are: 1. is it ok to take diazepam with tambocor? 2. Will the diazepam have any effect on my EKG since it works to relax muscles? The pharmicist said to ask my doctor but he hasn't returned my calls. thank you very much.
Posted by CCF CARDIO MD JMF on June 15, 1999 at 16:05:17
Dear Bob,
Thank you for your question. It is always important to be aware of drug-drug interactions while on any cardiac medication. In this case it is o.k. to take the diazepam prior to your test as a single dose prior to the procedure. Diazepam does have potential cardiac effects, but if you take it just prior to your test you will be monitored throughout. I would not recommend long term use of diazepam in combination with tambocor unless this were closely monitored.
I hope this has been useful. I wish you the best of luck. Feel free to write back.
Information provided here is for general purposes only. Specific questions should be addressed to your own doctor. If you would like to make an appointment at the Cleveland Clinic Heart Center, please call 1-800-CCF-CARE or inquire online by using the Heart Center website at www.ccf.org/heartcenter. The Heart Center website contains a directory of the cardiology staff that can be used to select the physician best suited to address your cardiac problem.
Posted by bob on June 15, 1999 at 18:09:36
thank you for such a speedy response. I'm just curious though (i'm a scientist), would diazepam have any effects or potential effects on an EKG since it works on muscles and if so, what would they be? thank you once again. Bob
Posted by CCF CARDIO MD JMF on June 15, 1999 at 19:18:27
Dear Bob,
In high doses, diazepam can have significant effects on the ecg and cause bradycardia (slow heart rates) or arrhythmia.
I hope this informaion is of assistance.
jmf
