Clonidine can cause fatigue/loss of stanima but so can stress. My guess is that if you can't shake out the fatigue with exercise, it is from the clonidine. That is a pretty low dose. There are many other drugs that are often used to treat anxiety -- clonidine is not used that often, but i guess if it works, it works. If the side effects are intolerable, it might be worth trying an SSRI like paxil, zoloft, effexor, etc.