PVCs - where do we stand

Dears,

Please have a look at these 2 studies that talk about PVCs and their Prognostic Significance in absence of heart disease i.e. in healthy heart people, do carry a negative prognosis. The studies are

• Relation of Ventricular Premature Complexes to the Risk of Sudden Cardiac Death: http://www.mendeley.com/research/left-ventricular-architecture-and-survival-in-africanamericans-free-of-coronary-heart-disease-from-the-atherosclerosis-risk-in-communities-aric-study/

• Premature Ventricular Complexes and the Risk of Incident Stroke: http://www.mendeley.com/research/metabolic-syndrome-clusters-and-the-risk-of-incident-stroke-the-atherosclerosis-risk-in-communities-aric-study/I know that smoking, hypertension, diabetes, family history, age are established and proven risk factors to develop future heart diseases…

my questions:

1- Based on the above studies, can we consider PVCs as an additional risk factor for future heart diseases, like CAD?2- If PVCs are now risk factor, does this apply on healthy people or those with known heart diseases?
3- Based on these studies, where do you rank the PVCs risk – if any - in compare to other risk factors….NO RISK, Slightly higher, very high in compare to those without PVCs.
4- After adjusting other factor, will my PVCs increase my risk of developing heart diseases in the future based on these studies and therefore, we should not consider PVCs harmless anymore.  

BR,"