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Extended treatment for Hep C Type 2
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Extended treatment for Hep C Type 2

Is there any research on the benefits of extending Pegasys and RibaPak treatment for hep c type 2 from 24 weeks to 36 weeks? My doctor is recommending 36 weeks and my insurance will only pay for 24. Thanks, Coop
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387294_tn?1207623785
My understanding is that 24 weeks is standard for type 2, the easiest to treat.  Is there a reason that he thinks it would help.  Is the doctor concerned about any factors specific to you (fibrosis level, race, weight?....)  Anyway, I hadn't heard this recommendation for type 2, type 3 is getting new strategies though.
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446474_tn?1404424777
This may help if you are a "slow responder" (undetectable between Weeks 4 &12...

"Understanding HCV Nonresponse and Identifying Candidates for Retreatment
Source: New Management Strategies for HCV Nonresponders and Relapsers"
By: Mitchell L. Shiffman, MD - Chief of the Hepatology Section and Medical Director of the Liver Transplant Program at the VCU Medical Center for over a decade.


"Approximately 25% of patients with genotypes 2 or 3 do not achieve an RVR but later achieve undetectable HCV RNA between Weeks 4 and 12. It is important to recognize that only 49% of patients with this response achieve an SVR when treated for 24 weeks.[3] It is therefore rational to assume that prolonging the duration of therapy from 24 to 48 weeks in these slow-to-respond genotype 2 and 3 patients may reduce relapse and enhance SVR rates, and a retrospective analysis supports this hypothesis.[21] Unfortunately, no prospective studies have yet addressed this important issue."

3. Shiffman ML, Suter F, Bacon BR, et al. Peginterferon alfa 2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3. N Engl J Med. 2007;357:124 134.
21. Willems B, Hadziyannis SJ, Morgan TR, et al. Should treatment with peginterferon plus ribavirin be intensified in patients with HCV genotype 2/3 without a rapid virological response? Program and abstracts of the 42nd Annual European Association for the Study of the Liver; April 11-25, 2007; Barcelona, Spain. Abstract 8.

Cheers!
Hector
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3122657_tn?1357436202
Hello everyone I'm new here but have been reading for about 2 months now and so glad I found some people that r going through what I'm about to endure not that I'm glad for anyones illness but glad u all came here to help us new people out I'm 45 femail  hepatitis c type 2 getting ready to start treatment sometime next week on pegasys can someone please tell me this stuff is not gonna kill me I'm very scared never even been sick before
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